[PDF] The Acid-Catalyzed and Uncatalyzed Hydrolysis of Nitriles on

One of the best methods to synthesize carboxylic acids is the hydrolysis (acid- or base-catalyzed) of nitriles which occurs in two steps through the intermediate amide (eq 1) Thus, the relative rates of nitrile hydrolysis correlate linearly with anticipated nitrile basicity



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The Acid-Catalyzed and Uncatalyzed Hydrolysis of Nitriles on

One of the best methods to synthesize carboxylic acids is the hydrolysis (acid- or base-catalyzed) of nitriles which occurs in two steps through the intermediate amide (eq 1) Thus, the relative rates of nitrile hydrolysis correlate linearly with anticipated nitrile basicity



[PDF] Theoretical study of nitrile hydrolysis by solid acid catalysts

1 jan 2000 · Subject headings: reaction mechanism; hydrolysis/ nitrile/ quantum chemistry catalyze both acid and base hydrolysis reactions (18) Its active 



[PDF] NF Jain and CE Masse Carboxylic acid - thieme-connectde

Hydrolysis of carboxylic acid esters, amides, and nitriles can be either catalyzed by acid or base Synthesis by nitrile hydrolysis is widely employed because the 

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