[PDF] [PDF] Testing a New Alcohol-Free Hand Sanitizer to Combat Infection

1 août 2011 · antimicrobial agent benzalkonium chloride This formula is known as a surfactant , allantoin, and benzalkonium chloride (SAB) sanitizer



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unique non-drying, moisturizing and conditioning formulation is NSF Approved E3 for no-rinse hand sanitizing for food handlers sustained degerming activity than gelled alcohol gel hand sanitizers that actually ces/uc m078792 pdf



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[PDF] Testing a New Alcohol-Free Hand Sanitizer to Combat Infection

1 août 2011 · antimicrobial agent benzalkonium chloride This formula is known as a surfactant , allantoin, and benzalkonium chloride (SAB) sanitizer



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AU G

UST!998.VOL68.NO2

.Dyer.Gerenraich•\Va;/hont.r• ol l ow in guniversalprecautionsisanintegraI partofORstaffmembers"responsibilitiesin pe r i oper a tivepatientcare.Theprecautions ma n d a t eroutinehandwashingwithsoapand wa terbeforeandafterallpatientcontact,and esp e ci a ll ybeforeinvasiveprocedures.Although i nt e n d edtoreducetheposroperarieriskofinfec- ti o cau r io n s v i n c l ud in ghandwashing,arefollowed on ly55%oftherimeinthenation"shospitals." Th econtributingfactorsbehindthisinsuffi- cie nthandwashingaremanifold:however,identi- tiedprincipalcausesincludethefollowing. s i vepatientload.Conservativeestimatesindi- ca t ethatphysiciansattendto20to30patients p e rday,andotherhealthcarepersonnel(eg. nu r s e s pe rday. u m eofpatientscausesdrynessandsubsequent mic r oa bra sion softheskin." torecoverbetweenwashings. T h es efactors,amongothers.haveledtoagreat in c r e aseintheuseofrinse-freeinstanthandsani- tiz e r sasasupplementtoproperhandwashingwith s oapandwater. T h emostwidelyusedhandsanirizersaregels a n dfoams.thatrelyonalcoholasthemainantimi- c r o bi alingredient.Alcohol,however.solubilizes a n dstripawaysebumandlipidsthatguardagainst ba c t e r ialinfectionsoftheskin.";Externiveuseof alco h ol co n tai n inghandsanitizcrsactuallyincreases t ease ca u si n gbacteria.Thissitua- tioncanincreasethechances ofspreadingdiscase-causing m i c r oo r ga n is m samongpatients. Th ethreatofspreadingdis- easecouldbeavoidedbyusing al c ohol f r e ehandsanitizersthat comple m en t .ratherthancompro- mis e .thenaturalbarrierfunc- tionoftheskin.Anacceptable alcohol-freeformulawould r e quireanantimicrobiaJagent thatkillsitwidevarietyofdis- ea se c au s i ngmicroorganisms, inc l udin ggram-positiveand gram n ega t i vebacteria.fungus, andmolds.Thisformulaalso wouldneedtoallowtheactive ingr e d i enttopenetratetheskin wh i l eminimizingskinirritation.ABSTRACT constrain t s co r sup p ch l conta i t r rlz e 239
25
1. 239
AORN J OU R NAL A UGU S

T1998,VOL68,NO2

•Dyer»Gerenraich•Wadhams·

Su c haformulaisobtainedbycombiningcer- t a a n ti m icrob ialagent.benzalkoniumchloride.This b e n z alk on iumchloride(SAB)sanitizer.

ESTAaLISH

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NGTHEHYPOTHESIS

B as e donthisinformation,researchersat Wo od w a r dLaboratories.Inc.LosAlamitos,Calif, h y po th es i z e dthattheprolongeduseofalcohol-con- ta in i nghandsanitizerswouldbelesseffectiveat d e g ermin gtheskinthananalcohol-freeSABsani- t iz e r .Totestthis,theyusedaprotocolvalidatedby th eUSFoodandDrugAdministration(FDA)for th h a c a l l ytofestthedegermingeffectiveness-ofhand- w a s hpreparationswithextendeduseandisaccept- ma n cetesting>

UTERATUREREVIEW

Th eliteraturereviewforthisstudyindicated th a int e nd e dfordegerrningskinwithouttheaidofrins- i n gwithwater.Thistypeofproducthassteadily gain e dpopularityinprofessionalcirclesasasup- p le m e n t[0handwashingwithsoapandwater.The t y p esofrinse-freehandsanirizersgenerallyare gr oupe dintotwobroadcaregorie

•alcohol-basedproductsand

•alcohol-freeproducts,

Theneedforimmediateandpersistent

a t pr epa r a t io nbyitsdefinitiunofapersonnel di0infectanr: anon-!rrifariug.onIimicrobial-coutaining p r e p a r a ti o ndesigned[orfrequentuseand whi c hwillreducethenumberoftransient mi croorgan iquotesdbs_dbs17.pdfusesText_23