19 7 Nucleophilic Addition of Grignard Reagents and Hydride Reagents: Alcohol Formation ▫ Treatment of aldehydes or ketones with Grignard reagents
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[PDF] Lecture 4: Nucleophilic Addition Reactions of Aldehydes and Ketones
The addition of carbon nucleophiles into aldehydes and ketones provides one of the most effective ways of forming new C−C bonds, as well as alcohols Many types of carbon nucleophiles have been developed for this purpose Organolithium reagents and Grignard reagents are two of the most important and widely used
[PDF] Nucleophilic addition to the carbonyl group
We will frequently use a device like this, showing a reaction scheme with a mechanism for the same reaction looping round underneath The reagents and
[PDF] Chapter 16 Aldehydes and Ketones: Nucleophilic Addition Reactions
19 7 Nucleophilic Addition of Grignard Reagents and Hydride Reagents: Alcohol Formation ▫ Treatment of aldehydes or ketones with Grignard reagents
[PDF] Reactions of Ketones and Aldehydes Nucleophilic Addition
Nucleophilic Addition of Hydride Reagents: Alcohol Formation Treating an aldehyde or a ketone with NaBH 4 or LiAlH 4 , followed by water or some other
[PDF] Aldehydes and Ketones: Nucleophilic Addition to the Carbonyl
Addition of Grignard Reagents (Chapters 14 5-14 6) 120 17 6: Principles of Nucleophilic Addition: Hydration of Aldehydes and Ketones Water can reversibly
[PDF] Chapter 19 Aldehydes and Ketones: Nucleophilic Addition Reactions
19 ○ Treatment of aldehydes or ketones with Grignard reagents yields an alcohol ○ Nucleophilic addition of the equivalent of a carbon anion, or carbanion
[PDF] Worksheet – Nucleophilic Addition and Substitution A variety of
Reagents, like H-OH and H-OR(alcohols) can add across the C=O bond of aldehydes and ketones The acid catalyzed mechanism is very similar to the addition to
[PDF] 16: Addition and Substitution Reactions of Carbonyl Compounds
Magnesium, Lithium and Zinc Reagents Addition Addition of Organometallic Reagents In nucleophilic acyl addition reactions, the nucleophile binds to the
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