[PDF] Antimicrobial Resistance: Tackling a crisis for the health



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Antimicrobial Resistance: Tackling a crisis for the health

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Antimicrobial

Resistance:

Tackling a crisis

for the health and wealth of nations

The Review on Antimicrobial Resistance

Chaired by Jim O'Neill

December 2014

Contents

The Review

2

What is antimicrobial resistance?

3 The economic cost of drug-resistant infections 6 resistance: a return to the dark age of medicine? 11

Future work: already we see cause for optimism

14

The Review on Antimicrobial Resistance, Chaired by Jim O'Neill23The Review on Antimicrobial Resistance, Chaired by Jim O'Neill

The Review

The UK Prime Minister announced a Review on Antimicrobial Resistance in July, calling for ideas to bring this growing threat under control. This is the Review a^xYflaea[jgZaYdj]kaklYf[] 9EJ!akfgllY[cd]\& We believe that this crisis can be avoided. The cost of taking action can be small especially for emerging economies, including the so-called BRIC nations, who will need to make improved investments in their health infrastructure and build industries that leapfrog to the next generation of innovation. klYjlaf_xoal`l`akhYh]j& 1. The impact of antimicrobial resistance on the world's economy if the problem is not tackled. 2. How we can change our use of antimicrobial drugs to reduce the rise of resistance, including the game-changing potential of advances 3. How we can boost the development of new antimicrobial drugs. 4. The potential for alternative therapies to disrupt the rise in resistanc e and how these new ideas can be boosted. 5. The need for coherent international action that spans drugs regulation, and drugs use across humans, animals and the environment. We approach our goals with a blank sheet of paper and open minds. We want to hear from bright and innovative minds across all countries and disciplines, starting with the hard-earned experience of physicians, healthcare workers and their patients.

The Review on Antimicrobial Resistance, Chaired by Jim O'Neill23The Review on Antimicrobial Resistance, Chaired by Jim O'Neill

What is antimicrobial resistance?

In 1928 a piece of mould fortuitously contaminated a petri dish in Alexander Fleming's Laboratory at St Mary's Hospital London, and he discovered that were discovered and went on to revolutionise healthcare, becoming the bedrock of many of the greatest medical advances of the 20 th \]Y\dqaddf]kk]kkm[`Ykhf]megfaYYf\lmZ]j[mdgkak L:![gmd\Z]lj]Yl]\]quotesdbs_dbs19.pdfusesText_25