COMPLEMENT INHIBITORS (SOLIRIS ULTOMIRIS™

Complement Activators Activators start the domino effect 9 Early Steps The initial steps vary between pathways Dependent on activating substance C3 convertase quickly forms in all paths to cleave C3 Watch this well-done animation on the activation of complement, the steps in the complement pathways, & the functions of complement 10 Late Steps

Two’s Complement - RIT

This is the two’s complement representation of the negative integer EXAMPLE: Find the two’s complement of 17 Step 1: 17 10 = 0001 0001 2 Step 2: Take the complement: 1110 1110 Step 3: Add 1: 1110 1110 + 1 = 1110 1111 Thus the two’s complement for -17 is 1110 1111 2 It begins on the left with a 1, therefore we know it is negative Now

Complement determinations in human disease

complement proteins have been purified, and many of the respective genes have been identified The complement cascade is a dual-edged sword, causing protection against bacterial and viral invasion by promoting phagocytosis and inflammation

Sentence Patterns II: Locating Objects and Complements

a linking verb is called a subject complement, because it completes—or complements—the subject A subject complement can be a noun or adjective, or it can be a phrase functioning as one of these parts of speech Example: Today is the first day of spring The air is fragrant V SC V SC Transitive Verbs

Complements, Adjuncts (& Specifiers)

The complement/adjunct distinction in VPs John [VP often eats apples with a fork] adjunct head complement adjunct In VPs, the direct object is always the complement (Almost) everything else is an adjunct (Exception to the rule: the verbs give and put take two complements a NP and PP )