[PDF] BIOCHEMISTRY OF THE SPHINGOLIPIDES*



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Sphingolipids: metabolism and cell signaling

376 carbohydrate moieties are often signatures for particular cell types, and mediate inter- actions with complementary ligands, such as extracellular matrix proteins and receptors



BIOCHEMISTRY OF THE SPHINGOLIPIDES*

the precipitated sphingolipides were removed by filtration, washed once with acetone, and air-dried The product was a white powdery material weighing 2275 gm (range 2000 to 2500 gm for spinal cord, 1300 to 1600 gm for brain) In view of the few data in the literature on the composition of the sphingo-



BIOCHEMISTRY OF THE SPHINGOLIPIDES

cedure of Klenk and Leupold (17) The sphingolipides were dissolved in 10 volumes of hot glacial acetic acid, and the solution was allowed to stand overnight at room temperature The solution was filtered by suction, and the solid was washed with acetone and then dried in a desiccator connected to an aspirator



OF EXTRACELLULAR SPHINGOLIPIDES

Mostsphingolipides are complicated molecules composed of at least three components; the best knownexamples are sphingomyelin, the cerebro-sides, gangliosides, and phytoglycolipides Some simpler sphingolipides, the ceramides, have also beendescribed, in which only the aminogroup is in the combined form; N-lignocerylsphingosine is



Handout 19 - Membrane Lipids and Sphingolipids

Handout 18 Membrane Lipids & Sphingolipids 3 3 Glycoglycerides (i e , glycolipids) are the most abundant glycerolipids in nature a sn-3 carbon contains galactose in most plants



Role of sphingolipids in muscle atrophy

sphingolipides, et les autres médiateurs sphingolipidiques peuvent s'interconvertir, ce qui complique considérablement l'étude de leurs fonctions Le céramide peut être produit par deux voies différentes: la voie de synthèse de novo, et l'hydrolyse de la sphingomyéline membranaire catalysée par les sphingomyélinases



UE1 : Biochimie - CERIMES

Pour en savoir plus : Sphingosine : majoritaire chez les animaux (90 des sphingolipides)-phytoshingosine (végetaux) : 4-OH sphinganine Acide gras Précurseur : sphinganine (forme saturée), synthétisée à partir du palmitoyl CoA et de la sérine Spingosine : diol-amine à 18 atomes de carbone ; 1 double liaison trans (C4) diol-amine



Lipids and Membranes - Saddleback College

9 Explain the difference in melting points of vegetable oils vs animal fats 10 Distinguish phospholipids from glycolipids 11 Distinguish glycerophospholipids from sphingophospholipids



The Lipids: Triglycerides, Phospholipids and Sterols

The Lipid Family Triglycerides (fats and oils) Predominate in the body (99 ) and in foods (95 ) Composed of Carbon, Hydrogen and Oxygen 9 kcalories per gram

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