[PDF] Vemlidy, INN-tenofovir alafenamide



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Reference ID: 4010360

VEMLIDY is a hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitor and is indicated for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease(1)



VEMLIDY: The only oral antiviral for chronic HBV infection in

VEMLIDY: The only oral antiviral for chronic HBV infection in adults without required renal dosage adjustment1-4 Dosing for • One pill VEMLIDY1 Pill is to scale eCrCl ≥50 mL/min l 30-49 mL/min l 10-29 mL/min* ESRD on chronic hemodialysis



DOSAGE FORMS AND STRENGTHS --------------------- HIGHLIG

VEMLIDY is indicated for the treatment of chronic hepatitis B virus (HBV) infection in adults with compensated liver disease [see Clinical Studies (14)] 2 DOSAGE AND ADMINISTRATION 2 1 Testing Prior to Initiation of VEMLIDY Prior to initiation of VEMLIDY , patients should be tested for HIV -1 infection VEMLIDY



Vemlidy, INN-tenofovir alafenamide

efficacy of Vemlidy 25 mg compared with tenofovir disoproxil fumarate 300 mg in HBeAg-negative subjects with Chronic hepatitis B GS-US-320-0110 is a an ongoing Phase 3, 09/11/2017 28/05/2018 SmPC and PL The efficacy and safety of Vemlidy in patients with chronic hepatitis B are based on 48 and 96-week data from two



Vemlidy, INN-tenofovir alafenamide

Vemlidy International non-proprietary name: tenofovir alafenamide Procedure No EMEA/H/C/004169/0000 Note Assessment report as adopted by the CHMP with all information of a commercially confidential nature deleted



Vemlidy - Optum RX

• Vemlidy is a targeted prodrug of tenofovir Data show that Vemlidy has a greater plasma stability and ability to deliver tenofovir to the liver, hence a lower dose can be given than Viread ® (tenofovir disoproxil fumarate) • The safety and efficacy of Vemlidy were based on two 48week clinical studies of patients with chronic -

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