Monitoring NEFA and BHBA serum levels in transition cows to
Why NEFAs? •Circulating NEFA levels are a good indicator of Negative Energy Balance because their presence represents active fat mobilization •During Negative Energy Balance, adipose is mobilized as NEFA and transported to the liver to be oxidized or reesterifed into triglycerides •Lower levels of NEFA indicate normal
Autocrine negative feedback regulation of lipolysis through
effect of FFAR4, plasma NEFAs and glycerol were increased in FFAR4-deficient mice as compared to littermate controls despite having elevated insulin levels, and cAMP accumulation in primary adipocyte cultures was augmented by treatment with the FFAR4 antagonist conceivably by blocking the stimulatory tone of endogenous NEFAs on FFAR4
Non-esterified fatty acids in the ovary: friends or foes?
Keywords: NEFAs, Granulosa cells, Oocyte, Ovary, Metabolic diseases Introduction to the follicular physiology Ovarian follicles are a large but limited pool of complex miniature structures in the ovary They are originally as-sembled in the form of primordial follicles containing a single layer of flattened pre-granulosa cells surrounding
RESEARCH Open Access Over-expression of TLR4-CD14, pro
NEFAs were much higher in the obese vs normal weight/thin individuals (p =0 000) Conclusion: Adipose tissue used to be thought of as mere storage of fats and energy, but it has been revealed to be an important neuro-immune-endocrine organ Immune cells, stimulated by NEFAs, produce pro-inflammatory
Azahar Lopez, PsyD Chrislyn Nefas, MA
Azahar Lopez, PsyD Chrislyn Nefas, MA Program Manager Research Analyst IV August 26, 2017
Epidemiology and Pathophysiology of Diabetes Mellitus
lipid secretion of NEFAs[12] Obesity is often determined by the use of body mass index (BMI) Though obesity is correlated to diabetes in both men and women, women were more frequently diagnosed with diabetes in relation to obesity, whereas men were diagnosed at lower BMIs Body
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