Ac anti-filaggrine - Lab Cerba
Ac anti-filaggrine Lesanticorpsanti-(pro)filaggrine(appeléspluscommu-némentanticorpsanti-kératine,ouanti-stratumcor-neum) constituent une classe d’autoanticorps qui
Axis-Shield Anti-CCP FCCP600
For several years, it has been recognised that antibodies to anti-perinuclear factor (APF) and keratin (AKA) are highly specific for RA It was subsequently reported that both these antibodies reacted with native filaggrin and now are referred to as anti-filaggrin antibodies (AFA)
Open Access Identification of citrullinated α-enolase as a
of anti-filaggrin antibody epitopes is dependent on the pres-ence of citrulline, an amino acid derived from arginine as a result of a post-translational modification catalysed by the enzyme peptidylarginine deiminase (PAD) [6,7] These findings have been exploited in anti-cyclic citrullinated peptide (anti-CCP) assays, which are more sensitive
Diagnostic Performances of Anti-Cyclic Citrullinated Peptides
antibodies (anti-CCP) and anti-filaggrin antibodies (AFA) have been reported to be highly specific for RA (2, 12) These new serological tests have advantage of easy performance by con-
Autoantibody and metalloproteinase activity in early arthritis
occurrence of anti-citrullinated vimentin (a-Sa), anti-citrullinated α-enolase peptide 1 (a-CEP-1), anti-filaggrin (AFA), anti-heterogeneous nuclear ribonucleoprotein (a-hnRNP/RA33), and anti-carbamylated protein (a-CarP) an-tibodies, and evaluated metalloproteinase 3 and 9 (MMP3, MMP9) activity Subsequently, we evaluated the utility of
Filaggrin Mutations Associated with Skin and Allergic Diseases
The new engl and journal of medicine 1316 n engl j med 365;14 nejm october 6, 2011 FLG is located in the epidermal differentiation complex, a cluster of approximately 60 genes in-volved in
Monoclonal ANTI-FLAG M2, Clone M2 (F3165) - Data Sheet
Monoclonal ANTI-FLAG® M2, Clone M2 produced in mouse, purified immunoglobulin Catalog Number F3165 Product Description Monoclonal ANTI-FLAG M2 is a purified immunoglobulin, IgG1, monoclonal antibody, isolated from murine ascites fluid, that binds to FLAG fusion proteins 1 Unlike ANTI-FLAG M1 antibody, the M2
Commentary Citrullination, a possible functional link between
Anti-citrullinated protein antibodies can be detected (with the CCP2 assay) in up to 80 of RA sera with a speci-ficity of 98 Besides being very specific for RA, the anti-bodies can be detected very early in the disease and can predict clinical disease outcome Furthermore, the anti-bodies are produced locally in the inflamed synovium, sug-
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