[PDF] Daniel Paredes-Sabja, PhD



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Measures for the Prevention and Control of Clostridium

Clostridium difficile (C difficile) is a bacterium that causes inflammation of the colon, a condition known as colitis It is the most common cause of diarrhoea in hospitalised patients Up to 20 percent of hospitalised patients are colonised with C difficile, but only a minority experience symptomatic disease



Important clinical advances in the understanding of

Clostridium difficile Nature 2009; 458:11 76-1181 2 Kuehne SA, Cartman ST, Heap JT, et al The role of toxin A and toxin B in Clostridium difficile infection Nature 2010; 467:711 -713 3 Loo VG, Bourgault A-M, Poirier L, ei al Host and pathogen factors for • Clostridium difficile infection and colonization N Engl J Med 2011; 365: 1693



Clostridium difficile Web Resource Manual

Clostridium difficile Web Resource Manual Clostridium difficile (C difficile) bacteria live in the intestinal tract of humans and other animals People usually do not have symptoms of illness; however, C difficile infection (CDI)* can result if the bacteria overgrow in the intestinal tract



Clostridium difficile–Associated Disease: An Emerging Threat

Clostridium difficile strains can also be classified by toxinotyping studies Subtle sequence variations within the PaLoc accounts for the various toxinotypes of C difficile, of 301 Figure 1 Production of toxin A (A) and toxin B (B) by NAP1/027 (BI/NAP1) strains of Clostridium difficile (From reference 11 with permission ) 0 250 500 750 1000



Daniel Paredes-Sabja, PhD

1 Title: Clostridium difficile spore-host interactions: Defining the role of the collagen-like BclA exosporium proteins in Clostridium difficile spore-entry into intestinal epithelial cells and in the pathogenesis of the infection 1 Funding Agency: FONDECYT, CONICYT Role: Director Budget: USD $ 330,000 2



Clostridium difficile – A possible zoonotic link

Clostridium difficile (C difficile) er en sporedannende strikt anaerob bakterie Bakterien kan forekomme naturligt i tarmen hos mennesker og forskellige dyr, som heste, svin, kvæg, fjerkræ, geder, får, gnavere, hunde og katte C difficile smitter direkte via afføring, via person‐til‐person



HANDYAUDIT PUBLICATION SUMMARY - HandyMetrics

Reduce Healthcare Associated Clostridium Difficile Infections Stefania Cloutier¹, Barley Chironda², Yuka Hutton¹, Jennie Johnstone¹ St Joseph’s Healthcare Centre – Describes the important move to more accurate hand hygiene (HH) compliance rates (using HandyAudit)



Management of Public Health Incidents: Guidance on the Roles

CDI Clostridium difficile infection COBRA Cabinet Office Briefing Room CPHM Consultant in Public Health Medicine CHP Community Health Partnership CMO Chief Medical Officer CNO Chief Nursing Officer COMAH Control of Major Accident Hazards COPFS Crown Office and Procurator Fiscal Service CSA Common Services Agency

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