Essential components of the biosafety guidelines contain some or all the following, depending on the facility: bio-risk assessment and identification; specific biosafety measures, which cover the code of practice, physical plant such as laboratory design and facilities, equipment acquisition and maintenance, medical .
The Biosafety programme management monograph covers biosafety program management, the process of developing and implementing biosafety oversight at the organizational level.
This monograph describes the plan–do–check–act management cycle that allows a biosafety program to operate in a risk- and evidence-based way..
Standard engineering controls in BSL-1 laboratories include easily cleaned surfaces that are able to withstand the basic chemicals used in the laboratory.
BSL-2 laboratories are used to study moderate-risk infectious agents or toxins that pose a risk if accidentally inhaled, swallowed, or exposed to the skin..
The goals of the Biological Safety Program, referenced in this manual as the Biosafety Program, are to protect laboratory workers, the public, and the environment from potentially hazardous biological agents..
The words in bold type are defined in the Glossary.
The Biosafety Program Management guideline provides comprehensive guidance on how to develop, implement, and manage a biosafety program in facilities where human and terrestrial animal pathogens and toxins are handled and stored.
The guideline outlines the steps essential to the development and execution of a comprehensive biosafety program, which includes planning, implementing, reviewing, and improving the program.
This guideline is intended to be used in conjunction with the CBS.
Footnote 10
A detailed list of all abbreviations and acronyms used throughout this guideline is located at the beginning of this document.
Each word or term is spelled out upon first use in the guideline, with the abbreviation immediately following in brackets.
After its initial definition, the abbreviation is used exclusively throughout the remainder of the d.
Planning a biosafety program starts with determining an organization's needs (based on its program intent and risk assessments), identifying measures to mitigate risks, and determining the human and financial resources required to implement the identified mitigation measures.
The size and complexity of an organization will dictate the specifics of its biosafety program.
However, there are core elements that, when assembled on a strong foundation of planning and commitment, provide a solid framework for an effective program.
Implementation of these elements corresponds to the "do" phase within the PDCA cycle.
The core bi.
BSC\tBiological safety cabinet
Safety training should begin with an orientation session in which general safety policies and a positive attitude toward safety are introduced.
Written institutional safety policies should be discussed and the seriousness of biosafety impressed upon the students.
In Canada, the handling or storing of Risk Group 2 (RG2), RG3, and RG4 human pathogens or toxins is regulated by the Public Health Agency of Canada (PHAC) under the Human Pathogens and Toxins Act (HPTA) and the Human Pathogens and Toxins Regulations (HPTR).
Under the Health of Animals Act (HAA) and the Health of Animals Regulations (HAR), the PHAC and the Canadian Food Inspection Agency (CFIA) regulate the importation of animal pathogens or part of one (e.g., toxin), animals naturally or experimentally exposed to an animal pathogen or part of one (e.g., toxin), and animal products or by-products (e.g., tissue, serum), or other organisms carrying an animal pathogen or part of one (e.g., toxin).
•Preface
Effective implementation and management of the biosafety program requires thorough documentation of all core elements such that they are readily available to senior management.
The core elements of the biosafety program include:
A biosafety programme is an organization-wide system that includes ,biosafety elements that protect personnel, the public and the environment from exposure to hazardous biological agents.
When developing a biosafety programme, key considerations include:.
In a smaller organization, senior management may include:
