Biosafety issues definition

What is an example of a biosafety issue?
One example is Staph infection.
BSL-3 – These microbes are contagious through respiratory transmission and highly dangerous, potentially deadly.
Tuberculosis would fall under this biosafety category.
BSL-4 – These are highly contagious microbes that are generally lethal with no known treatments..
Why is biosafety regulation important?
It checks its primary aim for harmful biological agents, chemicals, toxins, and radiation.
With the advancement of Biotechnology and Genetic Engineerin, biosafety has gained importance for ensuring public and nature's safety..

What is an example of a biosafety issue?