Computed tomography nanoparticles

  • How are nanoparticles used in imaging?

    Nanoparticles can also act as specific delivery platforms loaded with other imaging elements to identify cancers.
    An example includes the liposome encapsulated gold nanoclusters functionalized with Her2 antibody to detect human breast cancer cells in serum and tissue by colorimetry..

  • What nanoparticle characteristic is most relevant for CT imaging?

    As gold is a metal with a high atomic number it provides better X-ray attenuation and hence is considered as a suitable candidate for CT imaging [49–51].
    Simple surface modification for achieving colloidal stability and enabling active targeting is an advantage of AuNPs in a comparison with other NPs..

  • What nanoparticles are used for imaging?

    Semiconductor nanoparticles (quantum dots (QDs)) and upconversion nanoparticles (UCNPs) have been used as fluorescent probes in optical imaging due to their high quantum yield and excellent photostability compared with organic dyes [8,9]..

  • As gold is a metal with a high atomic number it provides better X-ray attenuation and hence is considered as a suitable candidate for CT imaging [49–51].
    Simple surface modification for achieving colloidal stability and enabling active targeting is an advantage of AuNPs in a comparison with other NPs.
  • Gold nanoparticles (GNPs) are emerging as one of the most promising contrast agents for computerized tomography (CT) due to their remarkable properties including high X-ray absorption coefficient, low cytotoxicity, tailored surface chemistry, excellent biocompatibility, and unique surface plasmon resonance .
  • Nanotechnology in diagnostic imaging
    Nanoparticles are the front-drivers of such next-generation multimodal technologies because they provide abundance of surface area for functionalization of different reporters, surface ligands to facilitate site-specific localization and stimuli-responsive behavior.
Computed tomography (CT) is an X-ray based whole body imaging technique that is widely used in medicine. Clinically approved contrast agents for CT are  IntroductionNon-targeted nanoparticles for Targeted nanoparticles for CT
Nanoparticles have several advantages over small molecule CT contrast agents, such as long blood-pool residence times, and the potential for cell tracking and targeted imaging applications.
The currently approved computed tomography (CT) contrast agents for intravenous injection are iodinated small molecules.(1) For example, iohexol has a benzene  IntroductionNon-targeted nanoparticles for Targeted nanoparticles for CT

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