Femtosecond crystallography

  • What is time resolved femtosecond crystallography?

    Time-resolved serial femtosecond crystallography (TR-SFX) is defined by the study of biomacromolecular reactions observed with time resolutions as rapid as femtosecond-scale using SFX [15,21,22]..

  • Time-resolved serial femtosecond crystallography (TR-SFX) is defined by the study of biomacromolecular reactions observed with time resolutions as rapid as femtosecond-scale using SFX [15,21,22].
Serial femtosecond crystallography (SFX) represents a set of techniques developed to enable X-ray crystallography experiments at X-ray FELs, which encompasses multiple developments in sample introduction and data collection.
The most successful application of FELs for biology has been the method of serial femtosecond crystallography (SFX) where nano or microcrystals are delivered to the FEL beam in a stream of their mother liquid at room temperature, which ensures the replenishment of the sample before the next X-ray pulse arrives.

How XFEL is used in Femtosecond crystallography?

XFELs are unique light sources that can be used to explore matter at atomic length and femtosecond time scales

The increase in brightness along with ultra-short pulses has facilitated the appearance of a new application of XFEL technology in the field of structural biology via serial femtosecond crystallography (SFX) ,

What is Serial femtosecond crystallography?

Serial femtosecond crystallography is a rapidly developing method for determining the structure of biomolecules for samples which have proven challenging with conventional X-ray crystallography, such as for membrane proteins and microcrystals, or for time-resolved studies

What is the structure-mechanistic relationship in Femtosecond crystallography?

Time-resolved serial femtosecond crystallography The structure-mechanistic relationship found in biological reactions is rarely explained through resolution of a single, static structure

Instead, the dynamics between initial and final states embody the mechanism


Categories

Fedorov crystallography
Crystallographic feature
Serial femtosecond crystallography diffraction
Serial femtosecond crystallography software
Serial femtosecond crystallography membrane proteins
Serial femtosecond crystallography time-resolved
Serial femtosecond crystallography experiment
Gemmi crystallography
Geometrical crystallography symmetry elements
Generalized crystallography
Crystallographic geometries
Crystallography hexagonal lattice
Hematite crystallography
Helix crystallography
The crystallography of correlated disorder
Homomorphism crystallography
John helliwell crystallography
Goniometer head crystallography
Crystallography heavy metals
Crystallography wavelength