Cytology urine with reflex to fish

  • Is FISH test positive for bladder cancer?

    Fluorescence In Situ Hybridization
    The intended use is as an aid for initial diagnosis of bladder cancer in patients with hematuria and subsequent monitoring for tumor recurrence in patients previously diagnosed with bladder cancer.
    Positive findings on FISH often precede visual evidence of bladder tumor..

  • What does a positive FISH test indicate?

    Doctors use the FISH test to measure the amount of HER2/neu gene in each cancer cell.
    If the FISH test comes back strongly positive for HER2, it is much more likely that a drug called trastuzumab (Herceptin) will work.
    Trastuzumab targets the HER2 protein..

  • What does FISH test mean for urine sample?

    Fluorescence in situ hybridization (FISH) analysis is an FDA-approved, urine-based marker that assists in diagnosis and surveillance of invasive urothelial cancer.
    This article provides an overview and case study demonstrating the clinical use of this analysis..

  • What is the FISH in urine cytology?

    The UroVysion FISH test is designed to detect chromosomal abnormalities associated with urothelial cell carcinoma in voided urine specimens..

  • What is the FISH method of urinalysis?

    This test is designed to detect aneuploidy for chromosomes 3, 7, and 17 and loss of the 9p21 locus, via fluorescence in situ hybridization (FISH) in urine specimens from persons with hematuria suspected of having bladder cancer..

  • What is urine cytology FISH test?

    This test is designed to detect aneuploidy for chromosomes 3, 7, and 17 and loss of the 9p21 locus, via fluorescence in situ hybridization (FISH) in urine specimens from persons with hematuria suspected of having bladder cancer..

  • Fluorescence In Situ Hybridization
    The intended use is as an aid for initial diagnosis of bladder cancer in patients with hematuria and subsequent monitoring for tumor recurrence in patients previously diagnosed with bladder cancer.
    Positive findings on FISH often precede visual evidence of bladder tumor.
  • The urine sample can also be collected during cystoscopy.
    During this procedure, your provider uses a thin, tube-like instrument with a camera on the end to examine the inside of your bladder.
    The urine sample is sent to a lab and examined under a microscope to look for abnormal cells.
Feb 14, 2014Positive FISH predicts for recurrence and progression in NMIBC surveillance patients with suspicious cytology but negative cystoscopy. However,  AbstractIntroductionPatients and MethodsDiscussion
Feb 14, 2014To assess the ability of reflex UroVysion fluorescence in situ hybridization (FISH) testing to predict recurrence and progression in  AbstractIntroductionPatients and MethodsDiscussion

Does fish detect urinary urination (UC)?

Corresponding tissue biopsies, where available, were also evaluated by FISH.
Results:

  1. Sensitivity and specificity of cytology and FISH for the detection of UC was 54
8% and 92% and 50% and 88%, respectively.
Only one of seven false-positive urinary FISH results proved to be an "anticipatory positive" on extended follow-up.
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Does UroVysion fish correlate with cytology and tissue biopsies?

Methods:

  1. Urine samples from 89 patients were prospectively collected for simultaneous cytology and UroVysion FISH
  2. results correlated with concurrent biopsies and/or clinical or histologic follow-up data

Corresponding tissue biopsies, where available, were also evaluated by FISH.
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How Do I Prepare For A Urine Cytology Test?

You’ll need to take your urine cytology test after your first morning pee.
This is because cells that are held in your bladder for a long period of time, or overnight, can break down over time, which can make it difficult for a pathologist to look for certain cells under a microscope.
Thus, you don’t want your urine cytology test sample to be your .

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How Is A Urine Cytology Test Performed?

There are four general steps involved in a urine cytology test, including:.
1) Collecting the urine sample.
2) Processing the urine sample cells.
3) Examining the urine sample cells.
4) Sharing the results.
Here’s an explanation of the steps of a urine cytology test.
Collecting the urine sample Most urine cytology test samples are collected by the p.

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Is urinary cytology more sensitivity and specific than fish?

Conclusions:

  1. We found urinary cytology to be more sensitivity and specific than FISH in the detection of UC
  2. though the difference was not statistically significant

Up to 24% of HG UCs are FISH negative due to an absence of FISH-detectable abnormalities in the tumor cells.
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Is UroVysion a useful reflex test for a suspicious urine cytology diagnosis?

The objective of the current study was to evaluate the usefulness of UroVysion as a reflex test in patients with a suspicious urine cytology diagnosis.
The rationale was that a more aggressive workup might be indicated in patients with a suspicious cytology diagnosis and positive UroVysion test.

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What Should I Expect After A Urine Cytology Test?

It may take a while to get your test results.
Since there are limitations to urine analysis tests, your healthcare provider will likely ask you to have other tests or procedures to look for urinary system cancer.
Because of this, your provider may want to get the results of all the tests before they share the results with you.
Your provider will le.


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