This group had the least number of cases (3.1%) and had cytomorphologic features that overlap with carcinoma.
The cytological features include moderate to high cellularity, moderate degree of cellular pleomorphism and anisonucleosis, occasional macronucleoli, and frequent chromatin clumping [Figure 1c]..
Nowadays, it is used as part of the triple approach (along with clinical and radiologic findings) to confirm a benign diagnosis, as a conjugate to core needle biopsy to enhance the accuracy rate, solo for palpable breast lesions in one step clinic, for lymph node assessment and for lesions difficult to access by core Feb 23, 2023.
The IAC Yokohama system utilizes the following five categories: (1) insufficient/inadequate, (2) benign, (3) atypical, (4) suspicious for malignancy, and (5) malignant to stratify the risk of malignancy (ROM) based on the most recent literature (subject to future modification) and suggested management..
Breast FNA cytology doesn't give a definite diagnosis name to the lesion most of the time and also can't differentiate atypical ductal hyperplasia from low grade cancer or high grade in situ carcinoma from invasive cancer .
• The cytoplasm sometimes contains various pigments or inclusions. • The nuclei are bland and round to oval.
Multinucleated giant foam cells also occur. • Foam cells are usually associated with benign breast lesions and cysts but can also be seen in cancer. • Origin ? controversy .
Cellularity is usually high and the cytologic features are malignant (high N/C ratio, irregular nuclear contour, hyperchromasia, conspicuous nucleoli) Some special types of carcinoma can be specifically recognized or suspected, like mucinous, medullary-like, papillary .
Cytopathology of breast • Presenter:
