Cytology liquid

Although it was also varied among individual studies, sensitivity (76.4%-94.9%) and specificity (66.0% to 98.3%) of LBC were relatively higher than those of Pap test.
Sensitivity and specificity of HPV test were 57.8%-95.8% and 37.4%-93.1%, respectively.
Liquid-based cytology is a method of preparing samples for examination in cytopathology.
Liquid-based cytology is an alternative to the Pap test (smear test).
Both form part of a cervical cancer screening that can also include an HPV test and physical pelvis examination.

Background: Liquid-based cervical cytology was developed to improve the diagnostic reliability of Papanicolaou (Pap) smears. Conventional Pap smears can have false-negative and false-positive results because of inadequate sampling and slide preparation, and errors in laboratory detection and interpretation.

The sample is collected, normally by a small brush, in the same way as for a conventional smear test, but rather than the smear being transferred directly to a

History

For many years

Methods

• SurePath: In the SurePath method, the sample is vortexed, strained, layered onto a density gradient, and centrifuged

Comparison to conventional smear

Liquid-based cytology improves specimen adequacy

Liquid-Based Cytology (LBC) New technology for alternative and complementary forms of screening alterations in the cervix has recently been proposed, and one of these is known as liquid-based cytology (LBC).