Cytology non diagnostic

What is a non diagnostic Category 1?
Definition (Table 1, Category .
1. An FNAB specimen is considered nondiagnostic if it contains fewer than six follicular groups, each of which contains 10 or more cells.
What is a non diagnostic specimen?
In up to 10% of biopsies, a diagnosis cannot be made since there are too few cells and the result is called nondiagnostic.
In some cases, such as aspiration of a cyst where few cells would be present, this is expected.
In other nodules, a non- diagnostic results usually requires a repeat biopsy..
Not diagnostic. (medicine) Unsatisfactory for diagnosis, not characteristic of a particular disease.

May 11, 2021Fine-needle aspiration cytology (FNAC) is mainly performed for nodules showing suspicious sonographic features that may require thyroidectomy.

Non-Diagnostic Samples

There are many reasons for obtaining a non-diagnostic sample: 1

No Cytologic Abnormalities

Cells are present in normal numbers for the tissue aspirated and do not possess significant criteria of malignancy

Inflammation

Inflammatory responses are classified by the type of inflammatory cells within the lesion

hyperplasia/dysplasia

The strict definition of hyperplasia is an increase in the number of cells in a tissue; however

Neoplasia

Neoplasia is suspected when there is a population of tissue cells in an aspirate that are not expected to be there

What are the different types of cytologic interpretation?

The following are the general categories of cytologic interpretation: Non-diagnostic No cytologic abnormalities Inflammation Hyperplasia/dysplasia Neoplasia Note: Often more than one category is present, as inflammation can result in dysplastic changes in the surrounding tissue and inflammation often accompanies a neoplastic process

What is the next step in cytologic diagnosis?

If the sample has adequate cellularity and the cells are well-stained and well-preserved, the next step in cytologic diagnosis is the identification of the cell types and pathologic process that are present

It helps to ask a series of questions when working through smears: Is there evidence of hemorrhage?

Non-diagnostic means that a diagnosis could not be made from the tissue sample provided by your doctor. This can happen when the tissue sample is too small, is damaged during retrieval or processing, or because the cells in the sample were no longer alive at the time the sample was received in the lab.