1,25-dihydroxycholecalciferol - NCBI


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PDF Identification of 125-Dihydroxycholecalciferol aNew Kidney

A vitamin D metabolite 25-dihydroxy cholecalciferol is further hydroxylated by kidney before acting as a hormone on target tissues The structure of this kidney metabolite is now described

PDF 125-dihydroxycholecalciferol: endocrinology meets the immune

125-Dihydroxycholecalciferol: Type 1 diabetes: NOD mice DC dendritic cells; 125(OH)The activated form of vitamin D 125-dihydroxychole-2 D 3 125-dihydroxycholecalciferol; NOD non-obese diabetic; Th T-helper calciferol (125(OH) 2D 3) is well known for its effects on Ca and bone metabolism but also non-classical effects of the

  • Does cholecalciferol have immunomodulatory effects?

    Previous work has demonstrated that, besides its effects on Ca and bone metabolism, the active form of cholecalciferol, 1,25-dihydroxycholecalciferol (1,25(OH)2D3), possesses pronounced immunomodulatory effects.

  • Does nephrectomy prevent bone calcium mobilization response to 25-hydroxycholecalciferol?

    1,25-dihydroxycholecalciferol: metabolite of vitamin D3 active on bone in anephric rats Nephrectomy prevents completely the bone calcium mobilization response to 25-hydroxycholecalciferol. In contrast it does not prevent this response to 1,25-dihydroxycholecalciferol.

  • How is 125-dihydroxycholecalciferol identified?

    The molecule has been identified as 1,25-dihydroxycholecalciferol by means of mass spectrometry, ultraviolet absorption spectrophotometry, and specific chemical reactions. Full text is available as a scanned copy of the original print version.

  • Which metabolite is more polar than 25-hydroxycholecalciferol?

    Proc Natl Acad Sci U S A. 1971 Apr; 68 (4): 803–804. A biologically active vitamin D 3 metabolite (“peak V metabolite”) more polar than 25-hydroxycholecalciferol has been isolated from chicken intestines in pure form as a mono (trimethylsilyl)ether derivative.

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Biosynthesis of steroid hormones Synthesis and hydroxylation

(Cholecalciferol) (25-Hydroxycholecalciferol) (1α,25-Dihydroxycholecalciferol) A CALCIOTROPIC STEROID HORMONE 20 -30 days The concentration of calcidiol in blood plasma informs of the body calciol saturation Seasonal variations are observed 25 -Hydroxylation of calcidiol is inhibited by the high concentrations of calcidiol and calcitriol


REPRODUCTION

calcitriol, (1α,25-dihydroxycholecalciferol), which is the most bioactive vitamin D isoform Circulating calcidiol can also be converted to calcitriol in other cell types and tissues, including the placenta (Shin et al 2010) Inactivation of vitamin D molecules results from the CYP24A1 hydroxylase, which converts both calcidiol


CYP27A1 expression in gilthead sea bream (Sparus auratus, L

produces 24R,25-dihydroxycholecalciferol It is noteworthy that, CYP24 also uses calcitriol to produce 1a,24R,25-trihydroxycholecalciferol, the first product in the C-24 oxidation pathway responsible for degradation of calcitriol Comparatively little is known in teleosts concerning ‘vitamin D 3 physiology’ Indeed, classical genome-mediated


維生素D與人體健康 - tsimorgtw

物技術資訊中心 (National Center for Biotechnology Information,NCBI) 所提供的PubChem資料庫19, 目前知道的維生素D有維生素D 2至D 7,維生素D 1 因被證實為混合物已較不常使用,維生素D 2及D 3 為人體內主要的維生素D,常見不同形式的維生 素D 2及D 3列於表一1,20,21。維生素D的


Publications for Christian Girgis 2020 2019 2015

Publications for Christian Girgis 2020 Girgis, C (2020) Vitamin D and Skeletal Muscle: Emerging Roles in Development, Anabolism and Repair Calcified Tissue


Article 1,25-(OH) D-24 Hydroxylase (CYP24A1) Deficiency as a

Article 1,25-(OH) 2D-24 Hydroxylase (CYP24A1) Deficiency as a Cause of Nephrolithiasis Galina Nesterova,* May Christine Malicdan,* Kaori Yasuda, †Toshiyuki Sakaki, Thierry Vilboux,* Carla


    IJMS

    IJMS

    Source: Free Full-Text

    Detailed Methods - Screening for Vitamin D Deficiency - NCBI Bookshelf

    Detailed Methods - Screening for Vitamin D Deficiency - NCBI Bookshelf

    Source:https://www.ncbi.nlm.nih.gov/books/NBK278935/bin/vit-d-prod-metab-moa_figure2.jpg

    Vitamin D: Production  Metabolism  and Mechanisms of Action

    Vitamin D: Production Metabolism and Mechanisms of Action

    Source:https://www.ncbi.nlm.nih.gov/books/NBK278935/bin/vit-d-prod-metab-moa_figure8.jpg

    Vitamin D: Production  Metabolism  and Mechanisms of Action

    Vitamin D: Production Metabolism and Mechanisms of Action

    Source:https://www.ncbi.nlm.nih.gov/books/NBK278935/bin/vit-d-prod-metab-moa_figure1a.jpg

    Vitamin D: Production  Metabolism  and Mechanisms of Action

    Vitamin D: Production Metabolism and Mechanisms of Action

    Source:https://www.spandidos-publications.com/article_images/ijo/47/3/IJO-47-03-1084-g00.jpg

    Differential antitumor effects of vitamin D analogues on

    Differential antitumor effects of vitamin D analogues on

    Source:https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid\u003d5280795\u0026t\u003dl



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