[PDF] 1,3-BUTADIENE




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[PDF] Draft Toxicological Profile for 1,3-Butadiene

5 sept 2012 · The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the toxic substances 

[PDF] Draft Toxicological Profile for 1,3-Butadiene

Toxicology Program (NTP), and EPA all classify 1,3-butadiene as a human carcinogen 1 6 HOW CAN 1,3-BUTADIENE AFFECT CHILDREN?

[PDF] Report on Carcinogens, Fifteenth Edition - 1,3-Butadiene

1,3-Butadiene is known to be a human carcinogen based on sufficient Toxicological Profile for 1,3-Butadiene NTIS Accession No PB93?110690

[PDF] Chapter 53 1,3-Butadiene - WHO/Europe

Toxicological effects High exposure concentrations of butadiene are required to cause acute toxicity in laboratory animals For example, Carpenter et al

[PDF] 1,3-BUTADIENE

Toxicological Profile for 1,3-Butadiene Atlanta, GA: U S Department of Health and Human Services Hazardous Substances Data Bank

[PDF] 1,3-Butadiene Reference Exposure Levels - OEHHA

Butadiene metabolites play a role in the toxicity of butadiene National Toxicology Program developed the first series of short-term studies to evaluate

[PDF] 1,3-BUTADIENE 39364_7butadienefaq.pdf

24/7 Emergency Contact Number:

1-888-295-5156

Revised: 09/2013

Page 1 of 2

1,3-BUTADIENE

What is 1,3

-BUTADIENE? 1,3 -Butadiene is a gas that has no color and a mild, gasoline -like odor. 1,3-Butadiene is made in nature and by human activity.

Where can 1,3

-Butadiene be found and how is it used? 1,3 -Butadiene is used to make petroleum products, such as man-made rubber for tires, and plastics. 1,3-

Butadiene is found in gasoline and vehicle exhaust. It is also found in smoke from cigarettes and wood fires.

1,3

-Butadiene is found at low levels in air near cities but sunlight removes it quickly. Since it is difficult to

measure, there is not enough information to know how it acts in soil and water.

How can people be exposed to 1,3-Butadiene?

You could be exposed to 1,3

-Butadiene through:

Breathing vapors if you work where 1,3-Butadiene is used or made, or if you live near a plant producing or

using it. Other people can be exposed through tobacco smoke, car exhaust or gasoline fumes. Drinking water or eating food containing 1,3-Butadiene. However, this is an uncommon way of being exposed. How does 1,3-Butadiene work and how can it affect my health?

Workers breathing large amounts of 1,3

-Butadiene causes short-term symptoms including eye, nose and throat irritation. Long -term effects are dizziness, sleepiness, lightheadedness, or fe eling confused.

Unconsciousness and death are possible. Long-term exposure to 1,3-Butadiene can result in heart, lung and

blood diseases. In humans, a link has been seen between 1,3-Butadiene and leukemia, a disease of the bone marrow. In groups of rubber workers, a more limited link was seen between 1,3 -Butadiene and lymphosarcoma and reticulosarcoma, which are cancers. 1,3 -Butadiene has been named as a probable cancer-causing substance.

Skin contact with liquid 1,3-Butadiene can cause irritation and frostbite. There is no information on health

effects from eating food or drinking water containing 1,3-Butadiene.

How is 1,3-Butadiene poisoning treated?

The exposed person should be removed from the source. Medical personnel should then be contacted for

treatment advice.

What should I do if exposed to 1,3-Butadiene?

Anyone exposed to high levels of 1,3

-Butadiene should be removed from the source immediately. Seek medical attention immediately. What factors limit use or exposure to 1,3-Butadiene?

Most of the population is exposed to very low levels of 1,3-Butadiene in the air we breathe. Exposure to higher

levels of 1,3

-Butadiene is very unlikely for anyone outside of the specific industries that use this chemical. Is there a medical test to show whether I've been exposed to 1,3-Butadiene?

There is currently no reliable medical test for 1,3 -Butadiene in the body.

24/7 Emergency Contact Number:

1-888-295-5156

Revised: 09/2013

Page 2 of 2

Technical information for 1,3-Butadiene

CAS Number: 106

-99-0

Chemical Formula:

C 4 H 6 Carcinogenicity (EPA): B2 - Possible human carcinogen.

MCL (Drinking Water): None

OSHA Standards: 1 ppm (2.2 mg/m

3 ) TWA; 5 ppm (11 mg/m 3 ) 15 min. Short Term Exposure Limit

NIOSH Standards: Lowest feasible concentration

ACGIH: 2 ppm (4.2 mg/m

3 ), 8 hr Time Weighted Avg (TWA)

References and Sources

Agency fo

r Toxic Substances and Disease Registry (ATSDR). 1993.

Toxicological Profile for 1,3

-Butadiene. Atlanta, GA: U.S. Department of Health and Human Services.

Hazardous Substances Data Bank. On

-line version:1,3-butadiene http://toxnet.nlm.nih.gov/cgi- bin/sis/search/f?./temp/~hdPXlc:1 (accessed 9/28/09) New Jersey Department of Health and Senior Services.

Right to Know Hazardous Substances Fact Sheets.

http://nj.gov/health/eoh/rtkweb/documents/fs/0272.pdf, Revised July 2007 (accessed 9/28/09)
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