[PDF] DIM-SAP-239 Principles of Molecular Cell Biology and Biotechnology




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[PDF] DIM-SAP-239 Principles of Molecular Cell Biology and Biotechnology

Course overview This course deals with the biology of cells of higher organisms, their structure and function; and processes operating in cells, 

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[PDF] DIM-SAP-239 Principles of Molecular Cell Biology and Biotechnology 43090_7010DIM_SAP_239PrinciplesofMolecularCellBiologyandBiotechnology.pdf Thisdocumentisabriefoutlineofthecourseanddoesnotreplacetheofficialprogramofstudy www.icai.comillas.edu1

DIMͲSAPͲ

239PrinciplesofMolecularCellBiologyandBiotechnologySEMESTER:Spring

CREDITS:7.5ECTS(Theory2hrs.during10weeksand5hrs.perweekduring5weeks;

Laboratory3hrs.perweekduring10weeks)

LANGUAGE:English

DEGREES:SAPIENSprogram

Courseoverview

Thiscoursedealswiththebiologyofcellsofhigherorganisms,theirstructureandfunction; andprocessesoperatingincells,suchastranscription,proteinbiogenesis,celladhesion, cellproliferation,cellcommunicationanddifferentiation.Experimentationwitheukaryotic cells,aswellasbiologydataanalysisandintroductiontoscientificcommunicationarealso introduced.

Prerequisites

Previousknowledgeonbiologyisadvisablebut

notmandatory.Coursecontents

Theory:

Lecturesaredividedintofourmainparts:

1. Introduction:eukaryotecells:organization,components,geneticinformationand

researchtools. 2. Cellmembranestructure,transportmechanisms,proteintransportpathways, metabolismandcellsignaling.

3. Cytoskeleton,extracellularmatrixandcellproliferationandadhesion.Cellular

communicationmechanisms.

4. Cancer.Researchapproaches.Laboratory:

Practicalsessionsincludethefollowingtopics:

Lab1. Methodsofimaging

Lab2. Geneticinformationanditstransmission:DNAandmitosis Thisdocumentisabriefoutlineofthecourseanddoesnotreplacetheofficialprogramofstudy www.icai.comillas.edu2

Lab3. Biochemistryofproteinfolding

Lab4. PartI:Theeffectofsugarstructureonfermentationrateinyeast.

PartII:Photosynthesis.

Lab5. Introductiontotissueculture

Lab6-9Introductiontomammal'scellcultureandexperimentation.Proliferation andapoptosis.Woundhealingassay.Differentiationassay.Protein extractionfromcellculture.

Textbook

EssentialCellBiology,4 th Edition.Authors:AlbertsB.,BrayD.,HopkinK.,JohnsonA.,

LewisJ.,RaffM.,RobertsK.andWalterP.

Othersources:

Molecularbiologyofthecell,5 th

Edition.Authors:AlbertsB.,JohnsonA.,LewisJ.,

RaffM.,RobertsK.,WalterP.

HistologyandCellBiology:AnIntroductiontoPathology,4 th

Edition.Author:

KierszenbaumA.

Molecularcellbiology,7 th Edition.Authors:LodishH.,KaiserC.A,BretscherA.,Amon

A.,BerkA.,KriegerM.,PloeghH.,andScottM.P.

Grading

Topassthecourseisnecessarytoachieveanoverallgradeofatleast5over10.

Theoverallgradeisobtainedasfollows:

• MidͲterm1:15% • MidͲterm2:15% • Laboratory:30%. • Teamresearchwork:15% • Finalexam:25%

Ifthestudentfailsthe

course,heorshecantakeasecondexaminationtopassthesubject andmustachieveatleast6over10togainapassoverall.
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