[PDF] Antibiothérapie curative 1 nov. 2015 Chirurgie : Claforan®





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Relais per os des antibiotiques en réanimation. Quand ? Comment

Les céphalosporines de troisième génération (céfotaxime ceftriaxone



Antibiothérapie injectable : relai per os infections de cathéters

19 sept. 2019 Erytromycine: cp pelliculé écrasable: pas de données gr solution buvable ... vancomycine IV : 1 gr X2/j et cefotaxime 2 gr X3/j.



Antibiothérapie curative

1 nov. 2015 Chirurgie : Claforan® 1-2g/8h + Flagyl® 500 mg IV/8h®± gentalline 5 mg/kg/j ... 4° choix : Oflocet® cp 200 mg 2 cps en une prise.



ANTIBIO - Guide

1 cp x 2/j pdt 14 j. Ciprofloxacine 500 mg x2/j PO pdt 14 j. Ceftriaxone IV IM**** 2g x 1/j ou Cefotaxime IV 2 g x 3/j pdt 14 j.



Diagnostic et antibiothérapie des infections urinaires bactériennes

11 déc. 2015 1 cp dans les 2 heures précédant ou suivant le ... pipéracilline+ tazobactam) et les C3G parentérales (céfotaxime ceftriaxone



Traitement des infections à staphylocoque

9 jui. 2016 Péni M ou céfazoline > BL + inhibiteur ou céfotaxime/ceftriaxone. 2. Eradication de la source / foyer(s) secondaire(s).



Claforan (cefotaxime)

CLAFORAN (cefotaxime for injection) may be indicated for the treatment of T + CP. 8 (21.1). T + ML. 7 (18.4) a T. (tobramycin). CT (cefotaxime).



Atelier référents en antibiothérapie

Cp. 1. Fang Medicine1990;69:307-16 ou céfotaxime 1 g x 3/j perf IV ou ceftriaxone 1 g/j IV ... Cefotaxime 1gX3:d OU ceftriaxone 1-2g/d.



CP - antibiotique français 17 oct

20 nov. 2019 Claforan. POUSSEL. KHÔNG KHÍ. B. Voir les antibiotiques. Une exposition de publicités médicales au musée de l'Imprimerie.



TDCalculsdoses pediatriquesCORRIGES

CLAFORAN 40 mg x 4 en IVL sur 15 minutes Donc 2 cp seront utilisés / prise (la moitié utilisée étant jetée) et 6 cp / jour. la boîte est de 20 cp.



PRODUCT MONOGRAPH - Sanofi

CLAFORAN (cefotaxime for injection) is a semi-synthetic 2-aminothiazolyl cephalosporin antibiotic for parenteral use In vitro studies indicate that the antibacterial action of CLAFORAN results from inhibition of cell wall synthesis It is stable against the action of most ?-lactamases





Claforan powder for Solution for Injection 500mg Claforan

Claforan powder for solution for injection 500mg contains sodium This medicine contains 24mg sodium (main component of cooking/table salt) in each vial This is equivalent to 1 2 of the recommended maximum daily dietary intake of sodium for an adult Claforan powder for solution for injection 1g contains sodium

  • What Is Claforan?

    Claforan is a cephalosporin (SEF a low spor in) antibiotic. Claforan is used to treat many kinds of bacterial infections, including severe or life-threatening forms. This medicine is also used to prevent infection in people having certain types of surgery. Claforan may also be used for purposes not listed in this medication guide.

  • Warnings

    You should not use Claforan if you are allergic to Claforan or another cephalosporin antibiotic (cefdinir, cefalexin, Keflex, Omnicef, and others).

  • Before Taking This Medicine

    You should not use Claforan if you have ever had a severe allergic reaction to any type of cephalosporin antibiotic (cefdinir, cefalexin, Keflex, Omnicef, and others). Tell your doctor if you have ever had: 1. an allergy to penicillin; 2. kidney disease; 3. liver disease; 4. a stomach or intestinal disorder such as colitis; 5. diabetes; or 6. heart...

  • How Should I Use Claforan?

    Claforan is injected into a muscle, or given as an infusion into a vein. A healthcare provider will give you this injection when Claforan is used to prevent infection from surgery. A healthcare provider may teach you how to properly use the medication by yourself to treat an infection. Read and carefully follow any Instructions for Use provided wit...

  • What Happens If I Miss A dose?

    Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. If you are receiving this medicine at a clinic, call your doctor if you miss an appointment for your injection.

  • What Happens If I Overdose?

    Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include weakness, cold feeling, pale skin, blue lips, or seizure (convulsions).

  • What Should I Avoid While Using Claforan?

    Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

  • Claforan Side Effects

    Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rashthat spreads and causes blistering and peeling). Claforan may cause serious side effects. Call your doctor at once i...

  • What Other Drugs Will Affect Claforan?

    Tell your doctor about all your other medicines, especially: 1. another injected antibiotic; or 2. a diuretic or "water pill." This list is not complete. Other drugs may affect Claforan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is the maximum daily dose of Claforan?

Premixed CLAFORAN Injection is intended for IV administration after thawing. The maximum daily dosage should not exceed 12 grams. If C. trachomatis is a suspected pathogen, appropriate anti-chlamydial coverage should be added, because cefotaxime sodium has no activity against this organism.

How do I use Claforan?

A healthcare provider will give you this injection when Claforan is used to prevent infection from surgery. A healthcare provider may teach you how to properly use the medication by yourself to treat an infection. Read and carefully follow any Instructions for Use provided with your medicine.

Can I take Claforan after reconstitution?

CLAFORAN may be administered IM or IV after reconstitution. Premixed CLAFORAN Injection is intended for IV administration after thawing. The maximum daily dosage should not exceed 12 grams.

What is Claforan infusion in Galaxy ® containers (pl 2040 plastic)?

CLAFORAN Injection in Galaxy ® Containers (PL 2040 plastic) is for continuous or intermittent infusion using sterile equipment. Store in a freezer capable of maintaining a temperature of -20°C/-4°F. Thaw frozen container at room temperature or under refrigeration (at or below 5°C).

Antibiothérapie curative

Antibiothérapiecurative

Protocolesetfichestechniques,version1.

01/11/2015

CommissiondesantiǦInfectieux.

Sommaire

Pages

1.1.Péritonitescommunautaires,

1.2.Péritonitesnosocomiales

1.3.Quandutiliserunantifongique?

1.5.InfectionàClostridiumdifficile.

4Ǧ9

5 6 7 8 9

2.Priseenchargedesinfectionsurinaires

2.1.

Situationscliniquescourantes

2.3.CystitedocumentéeàBLSE

associéesauxsoins(IUAS).

10Ǧ16

11 12 13 14

15Ǧ16

3.1.

Pneumonie

2.2.BPCO

17 18 19

5.Sepsissansported'entrée21

6.Prophylaxiedel'endocardite22

7.Priseenchargedesinfectionsvasculaires

7.1.

7.2.Lesschémathérapeutiques

7.3.Laduréedutraitement

23Ǧ26

24
25
26

8.Bonusagedesantibiotiquescritiques

5.1.

Lesbétalactamines

5.2.Lesfluoroquinolones

5.3.Lesantibiotiquesdedernierrecours

27Ǧ27

28Ǧ29

30
31

9.Vaccinationchezlesplénectomisé32

Rappelsdesbonnespratiques

bactériologiques,

Limiterladuréedestraitements

dansledossiermédical.

1. http://www.infectiologie.com/site/medias/_documents/ATB/infoǦantibio/infoǦantibioǦ2014Ǧ12Ǧ02.pdf

2. http://www.sfar.org/_docs/articles/RFESFAR2014ǦPriseenchargedesinfectionsintraǦabdominales.pdf

3. http://www.infectioǦlille.com/index.php/component/content/article/34ǦatbǦadulte.html?start=9

Remarquesgénérales:

prélèvementsperopératoires.

Schémasthérapeutiques

TableauxcliniquesMoléculesDurées

Sanssepsisgrave

Augmentin

+Gentalline

C3Ginjectables*+Flagyl

SiallergieTavanic

+Gentalline +Flagyl

IIAlocalisée:2Ǧ3j

IIAgénéralisée:5Ǧ7j

SepsisgraveouchocTazocilline

+Gentalline *Claforan ,Rocéphine

Posologiesetmodalitésd'administration

MoléculePosologie

Augmentin1Ǧ2gIV/8h

48Ǧ72H

Claforan

Rocéphine

1Ǧ2g/8h

1Ǧ2g/jenuneinjection

Tavanic500mg/12h(perfusionlentede60mn)

Flagyl500mg/8h

Tazocilline4gensapde4htoutesles8Ǧ6h

Remarquesgénérales:

prélèvementsperǦopératoires.

Schémasthérapeutiques

TableauxcliniquesMoléculesDurées

TTprobabilisteTazocilline

+Amiklin (si signesdegravité)

5Ǧ15j

Sepsisgrave Tazocilline

+Amiklin

Carbapénèmes*+Amiklin

si2FRdeBMR

Chocseptique Tazocilline

+Amiklin

Carbapénèmes*+Amiklin

si1FRdeBMR *Tiénam ouMéronème !!Invanz

Posologiesetmodalitésd'administration

MoléculePosologie

48Ǧ72H

Tiénam

Méronème

1g/6Ǧ8h(perfusionlentede60mn)

1g/12h(perfusionlentede30mn)

FacteursderisquedeBMR:

1. Traitementdansles3moisparuneC3Gouunefluoroquinolone,

2. Isolementd'uneEBLSEoud'unP.aeruginosarésistantauTiénam

3. Hospitalisationàl'étrangerdansles12mois,

4. VieenEHPAD/SLDETsondeurinaireàdemeureougastrostomie,

5. EchecdetraitementparC3G,fluoroquinolonesouTazocilline

6. Récidiveprécoce(15j)d'uneinfectiontraitéependantaumoins3JparTazocilline

Défaillancehémodynamique,

Sexeféminin,

ChirurgiesusǦmésocolique,

Antibiothérapiedepuisplusde48h.

Indiquésencasd'isolementaudirectou

est

Posologiesetmodalitésd'administation

MoléculePosologie

TriflucanJ1:800mgenuneinjectionde60mn

ApartirdeJ2:400mg/Jenuneinjectionde60mn

Cancidas

>80kg:70mg

Enuneinjectionde60mn

TableauxcliniquesMoléculesDurée

Sigmoidite

Ambulatoire:Augmentin

1Ǧ2g/8h

Chirurgie:Claforan

1Ǧ2g/8h+Flagyl

500mgIV/8h

±gentalline5

mg/kg/j

AllergieBL:Dalacine

600mg/8h+gentalline5mg/kg/j

7Ǧ14j

gentalline3j

Cholécystite(1)

Angiocholite(2)

Abcèshépatique(3)

AngiocholitepostǦCPRE

Rocéphine

2g/j+Flagyl

500mgIV/8h

AllergieBL:Oflocet200mg/8h+Flagyl

500mgIV/8h

±gentalline

5Ǧ7mg/kg/j

Tazocilline4g/6Ǧ8h+Amiklin20mg/kg/j

(1)5Ǧ7j (2)10Ǧ14j (3)6semaines ILA Claforan1Ǧ2g/8henprobabiliste,adaptationselonantibiogramme10j

Pancréatitesansinfection Pasd'antibiotique

Pancréatiteavecinfection Claforan

1Ǧ2g/8h+Flagyl

500mgIV/8h

±gentalline5mg/kg/j

Drainagechirugicalàdiscuter

14j

Salpingite Rocéphine

1g/j+Flagyl

500mgIV/12h

+Doxycycline100mg/12h14j

Letraitement.

Cassévèresou

Vancomycineperos250mg/6hpendant14j

MétronidazoleIV500mg/8h

2.S'ils'agitd'unepremièrerécidive:

3.S'ils'agitderécidivesmultiples:

VancomycinePeros250mg/6hpendant7j

PuisVancomycinePeros250mg/12hpendant7j

PuisVancomycinePeros250mg/48hpendant7j

PuisVancomycinePeros250mg/72hpendant14j

Schéma2:Dificlir

cpà200mg1cp/12hpendant10j

2.Priseenchargedesinfectionsurinaires.

1. http://www.infectiologie.com/site/medias/Recos/2014Ǧinfections_urinairesǦcourt.pdf

2. http://www.infectioǦlille.com/index.php/component/content/article/34ǦatbǦadulte.html?start=9

3. Saint.F.PréventionettraitementdeseffetsindésirablesassociésauxinstillationendoǦvésicaledeBCG.Progrèsen

urologie(2006),16,780Ǧ785.

4. http://www.infectiologie.com/site/medias/Recos/2015ǦRPCǦinfections_urinaires_associees_aux_soins.pdf

TableauxcliniquesMoléculesDurée

Cystitesimple

1°choix:Fosfocine

:1sachet

2°choix:Séléxid

cp200mg,2cps/12h

3°choix:Nitrofurantoine

cp50mg,2cp/8h

4°choix:Oflocet

cp200mg,2cpsenuneprise

Priseunique

5j 5j priseunique

Cystiteàrisquedecomplication*

Attendreantibiogrammesipasd'urgence,

Siattenteimpossible:

1°choix:Nitrofurantoine

cp50mg,2cp/8h

2°choix:Oroken

cp200mg,2cp/12h

3°choix:Oflocet

cp200mg,1cp/12h

Adaptationduttselonl'antibiogramme

7j 7j 5j

Bactériurieasymptomatique(même

sursondeurinaire

Pasdetraitement10j

Pyélonéphriteaiguesimple

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