[PDF] THIRD YEAR SEMESTER EXAMINATION Third Year B.Pharm

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THIRD YEAR SEMESTER EXAMINATION

Third Year B.Pharm. Semester-V

SUBJECT- BPH_C_501_T-Organic Chemistry-III

Practice questions

1. Skraup synthesis is used to synthesize which of the following heterocycles?

a. Isoquinoline b. Quinoline c. Indole d. Imidazole

2. Which of the following sentence is correct.

a. Pyridine is more basic than aniline b. Aniline is more basic than quinoline c. Pyridine and aniline is equally basic d. All of the above

3. Reaction of Imidazole with HNO3/H2SO4 gives following products.

a. 2-Nitroimidazole b. 4-Nitroimidazole c. 1-Nitroimidazole d. All of the above

4. Which of the following heterocycles is most aromatic in nature.

a. Furan b. Pyrrole c. Thiophene d. All of the above

5. Elctrophilic Substitution reaction in furan occurs at which position

a. 1st position b. 2nd position c. 3rd position d. All of the above

6. Reaction of Quinoline to 2-Aminoquinoline which if the following reagents is used

a. NaNH2 / Liquid Ammonia b. Sodium azide c. Ammonia d. None of the above

7. What is the name of starting material used for Paal-Knoor synthesis of Furan?

a. 1,4-diketo compound b. 1,5-diketo compound c. All of the above d. None of the above

8. Following is the correct order of aromaticity.

a. Thiophene > Pyrrole > Furan b. Thiophene < Pyrrole < Furan c. Furan > Pyrrole > Thiophene d. Pyrrole > Furan > Thiophene

9. Identify the product for following reaction.

a. Pyridine-3-carboxylic acid b. Pyridine-2,3-dicarbaldehyde c. Pyridine-N-oxide d. All of the above

10. Which of the following is Non-aromatic in nature.

a. 2,3-dihydropyrrole b. Piperidine c. 3,4-dihydrofuran d. All of the above

11. Identify the phenolic group containing amino acid from the following

a. Leucine b. Tyrosine c. Tryptophan d. Asparagine

12. A propylene polymer in which methyl groups have alternate positions along the chain of

the polymer is known as: a. Syndiotactic polymers b. Isotactic polymers c. Atactic polymers d. None of the above

13. Thermoplastics are polymers that are

a. Hard at room temperature but become soft and viscous when heated b. That are highly cross-linked c. Solidify into a hard, insoluble mass when heated d. All of the above

14. Reductive amination of pyruvic acid, using ammonia and NaBH4, gives which of the

following amino acids? a. Glycine b. Valine c. Alanine d. Proline

15. Isobutyrl group is used to protect which nucleic acid base:

a. Thymine b. Adenine c. Cytosine d. Guanine

16. Steroidal ester hydrolysis exhibits following order of reactivity:

a. Axial groups are hydrolyzed faster than equatorial groups b. Equatorial groups are hydrolyzed faster than axial groups c. Both axial and equatorial groups are hydrolyzed at the same rate d. The rate of hydrolysis is independent of the orientation of the group

17. Action of potassium acetaWHRQ-Tosyl derivative of cholesterol in aqueous acetone

gives: a. -Acetoxy-..-cyclocholestane b. -Acetoxy-.-cyclocholestane c. -Acetoxy-.-cyclocholestane d. .-Acetoxy-.-cyclocholestane

18. The hormone cortisone contains the steroid core as:

a. Estrane b. Andrsotane c. Cholestane d. Pregnane

19. %URPLQDWLRQRI.-Cholestan-3-one gives a

a. 5-bromo derivative b. 2-bromo derivative c. 4-bromo derivate d. 3-bromo derivative

20. Catalytic hydrogenation of steroidal ketones when carried out under neutral conditions

will give: a. Axial alcohol b. Trans-diaxial diol c. Equitorial alcohol d. Trans-di equatorial diol

Answers for MCQs:

1. (b)

2. (a)

3. (b)

4. (c)

5. (b)

6. (a)

7. (a)

8. (a)

9. (a)

10. (d)

11. (b)

12. (a)

13. (a)

14. (c)

15. (d)

16. (b)

17. (a)

18. (d)

19. (b)

20. (c)

THIRD YEAR UNIVERSITY EXAMINATION

AY 2020-2021

Third Year B.Pharm Semester V

SUBJECT - BPH_C_502_T- Pharmaceutics II

Practice Questions

1) Acacia is an emulsifying agent of a class of:

a) Surfactants b) Polysaccharides c) Sterol containing substance d) Finely divided solids

2) Ratio of oil: water: gum for Mineral oil Emulsion is

a) 4:2:1 b) 3:2:1 c) 1:2:1 d) 2:2:1

3) µ6PDOO particles in suspension seem to disappear and large particles grow after repeated

b) Ostwald ripening c) Gibbs equation d) Stokes Einstein Law

4) Pseudomonas aeruginosa can contaminate cosmetic products having pH:

a) 6-8 b) 3-5 c) 6-10 d) 3-11

5) Schedule M(II) of D and C Act:

a) lists the colors used in Cosmetics b) gives the guideline for manufacturing Cosmetics c) is a list of Cosmetic Products d) gives labelling details for cosmetic products

6) Oral pharmaceutical Suspensions are:

a) Thermodynamically stable b) Thermodynamically unstable c) kinetically unstable

7) Dispersed phase in a biphasic liquid is:

a) Internal phase b) External phase c) Emulsifier d) Viscolizer

8) An emulsifier having a HLB value of 12 promotes formation of:

a) o/w emulsion b) w/o emulsion c) microemulsion d) Multiple emulsion

9) Deflocculated suspensions tend to exhibit:

a) plastic or pseudoplastic flow b) dilatant flow c) plastic flow b) pseudoplastic flow

10) List of Cosmetic products to be manufactured as per recommended standards is

given in: a) Schedule M b) Schedule Q c) Schedule S d) Schedule M (II)

11) A stable suspension with a low rate of sedimentation can be obtained by:

a) by reducing the size of the dispersed particles and by increasing viscosity of the dispersion/continuous phase b) by reducing the size of the dispersed particles and viscosity of the dispersion/continuous phase

c) by increasing the size of the dispersed particles and viscosity of the dispersion/continuous phase

d) by increasing the size of the dispersed particles and by decreasing viscosity of the dispersion/continuous phase

12) Electrolytes such as KCl and NaCl are:

a) Flocculating agents b) Dispersants c) Deflocculating agents d) Wetting agents

13) DLVO theory explains:

a) Rate of sedimentation b) Wetting phenomenon c) Particle-particle interactions d) rate of precipitation

14) Permeation of drug through skin is directly proportional to

a) partition coefficient b) molecular size c) molecular weight d) particle size

15) Following is the dosage form intended for rectal administration

a) Tablet b) Capsule c) Lozenge d) Suppository

16) Following are the examples of Hydrocarbon bases except

a) ozokerite b) mineral oil c) petrolatum d) lanolin

17) Drug penetration through skin can be altered by:

a) by decreasing resistance of stratum corneum b) by changing hydration of stratum corneum c) by changing the structure of lipids d) All of the above

18) Following factors affect systemic absorption of drug following rectal administration except

a) pKa of drug b) lipid water partition coefficient c) colonic fluid d) gastrointestinal pH

19)Following are the commonly used suppository bases except:

a) Cocoa butter b) Gelatin c) Polyethylene Glycol d) Lanolin

20) Following are the objectives of performing sensorial testing except:

a. interpret responses to the product based on senses b. the testing is done to assess the overall acceptance of consumers c. Sensorial testing is done on cosmetic products d. sensorial testing is done to check the safety of product

21) Following is the commonly used propellant in aerosols :

a. Nitrogen b. Neon c. Hydrofluoroalkanes d. Oxygen

22) Following are the tests performed in sensitivity testing of cosmetic except:

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