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AM. ZOOLOGIST, 10:331-346 (1970).

Transpor

t

Equation

s an d

Criteri

a fo r Activ e

Transpor

t ALA

N R. KOCH

Department

of Zoology, Washington State University,Pullman, Washington 99163

SYNOPSIS

. The relation between driving forces and the flux of solutes that would be expecte d i n a passiv e syste m i s derived Thi s relatio n i s a differentia equatio n an d dif feren t solution s ar e obtaine d whic h appl y t o differen t experimenta l conditions

Solution

s ar e give n fo r th e case s o f pur e convectiv e flow diffusion electrophoreti c mobility balanc e betwee n diffusiv e an d electrica l forces an d transpor t i n th e presenc e o f bot h concentratio n an d voltae e differences .Many different criteria have been used fo r th e definitio n o f activ e transpor t pro cesse s acros s membranes Th e presenc e o f saturatio n kinetic s an d th e potentia l fo r competitiv e inhibitio n sugges t th e forma tio n o f a chemica l bon d betwee n th e trans porte d substanc e an d somethin g i n th e membran e a s a preliminar y ste p t o trans port

Stoichiometri

c couplin g o f transpor t t o oxyge n consumptio n an d inhibitio n o f transpor t b y metaboli c blockin g agent s sugges t tha t transpor t depend s o n cellula r supplie s o f energy

Compariso

n o f th e measure d transmembran e movemen t wit h tha t expecte d i n a non-livin g syste m ca n indicat e th e activit y o f a proces s tha t woul d no tquotesdbs_dbs17.pdfusesText_23