[PDF] Non-Invasive Cardiac Stress Testing



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The New York Mets: A Team Effort

their marketing game, the Mets stepped up to the plate – and the game was on The Team Ethic In a game situation, teamwork is essential As a member of the Mets behind-the-scenes team, the Xerox Graphic Communications Marketing group offered to lead and fund the 1:1 Lab program test Xerox brought in the Pente Corporation, an experienced



MET Levels of Common Recreational Activities

MODERATE 5–6 3 0–6 0 METs Noticeable increase Feels fairly easy to somewhat hard (e g , brisk walking) VIGOROUS 7–8 Greater than 6 0 METs Large increase in breathing & heart rate but not out-of-breath Feels somewhat hard to hard (e g , jogging, vigorous sports) *Intensity scale: On a scale of 0–10 where 0 = sitting and 10 = all-out effort



Non-Invasive Cardiac Stress Testing

Achieving ≥ 10 METS: Medical therapy as good as CABG no matter how bad the CAD 2 13 METS = Excellent prognosis, regardless of exercise response 1 Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE Exercise capacity and mortality among men referred for exercise testing N Engl J Med Mar 14 2002;346(11):793-801 2



Understanding and Interpreting an FCE

3 Effort Metrics Definitions •Consistency of Effort = Reproducibility - or the likelihood that an effort may be copied, duplicated, or produced as a close imitation, in a series of trials •Quality of Effort = Degree - or the extent, level, or scope of a subject's volitional exertion in maximal or repetitive testing



EPREUVES D’ EFFORT

Segmentation de l’épreuve d’effort Sujet sédentaire •P max Théorique 300 watts (302 W) •13 minutes d ’effort ( 8 à 20 min d’effort ) : • 3 min d’échauffement à 20 PMT : 60 Watts • 10 paliers de 1 minute • Incrément de 25 W ( 300W – 60w ) / 10min



Peut-on interpréter un test d’effort sous-maximal

test ’effort “sousmaximal” c’est e saoir s’il est vraiment sous-maximal On parlera de test sous-maximal lorsque l’effort a été interrompu précocement soit par l’opérateur soit par manque e motiation u suet et non pas en raison de signes cliniques ou ECG imposant l’arrêt e test ’effort oit être maximal ou limité par les smp



TREADMILL EXERCISE TESTING

common test used to assess cardiorespiratory fitness, especially in clini-cal settings The test is administered in three-minute stages until the client achieves 85 of his or her age-predicted maximum heart rate (MHR) In a clinical setting, the test is typically performed to maximal effort, to evaluate both fitness and cardiac function

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Non-Invasive Cardiac Stress Testing:

Choosing the Most Appropriate Test to Get the Most Diagnostic Benefit for Your Patient

JENNIFER BALLARD-HERNANDEZ

DNP, FNP/GNP/CVNP-BC, CCRN, CHFN, AACC, FAHA

CARDIOLOGY NURSE PRACTITIONER

VA LONG BEACH

Disclosures

program/presentation.

Objectives

modalities testing agents assessment, diagnosis, clinical management and prognosis

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What we will be reviewing:

Chest Pain

emergency department2 can lead to substantial consequences2 imperative

1.Hsiao CJ, Cherry DK, Beatty PC, Rechtsteiner EA. National ambulatory medical care survey: 2007 summary. Natl Health Stat Report. 2010; (27):1-32.

2.Bonow RO, Braunwald E. Braunwald's heart disease : a textbook of cardiovascular medicine. 9th ed. Philadelphia: Saunders; 2012.

Purpose of Stress Testing

potential symptom equivalents device therapy

Potential Complications

ventricular arrhythmia, and death) has been estimated to be about 1 in 25001

1. Gibbons RJ, et al. ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart Association Task Force on

Practice Guidelines. J. Am. Coll. Cardiol. Oct 16 2002;40(8):1531-1540.

When performing the chest pain work up,

You must have a method to your madness!

Step 1: Assess the Clinical Classification of Chest PainStep 2: Determine Pretest Probability of CADStep 3: Determine the Most Appropriate

Stress Test Modality

Step 1: Assess the Clinical Classification of Chest Pain

‡Substernal chest discomfort

‡Provoked by exertion or emotion stress

‡Relieved by rest or NTGTypical Angina

(definite) ‡Meets 2 of the above characteristicsAtypical Angina (probable)

‡Meets 1 or none of the typical anginal

characteristicsNoncardiac

Chest Pain

J Am Coll Cardiol. 2012;60(24):2564-2603. doi:10.1016/j.jacc.2012.07.012 Step 2: Determine the Pre Test Probability of Coronary Disease

Gibbons RJ, et al. ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart Association Task Force on

Practice Guidelines. J. Am. Coll. Cardiol. Oct 16 2002;40(8):1531-1540.

Pretest Likelihood of CAD in Symptomatic Patients

According to Age and Sex* (Combined Diamond/Forrester and CASS Data) Diagnostic power of stress testing is maximal when the pre-test probability is intermediate

Low CAD

ProbabilityHigh CAD

ProbabilityIntermediate

CAD Probability

High False

Positive RateOptimalHigh False

Negative Rate

Step 3: Determine Stress Test Modality

Choice of stress testing modality depends on many factors, including but not limited to:

Step 3: Determine Stress Test Modality

EXERCISE STRESS TESTING

Exercise Stress Testing

supply of oxygenated blood to myocardial cells is inadequate to meet demands increasing to maximal tolerance, can elicit cardiovascular abnormalities not present at rest, while aiding in the determination of the adequacy of cardiac function 1

1.Fletcher G et al. Circulation 2013;128:873-934Photo source: Ballard-+HUQMQGH]·V SHUVRQMO SORPR ŃROOHŃPLRQ

Exercise Stress Testing

all-cause death

1. Gibbons RJ, et al. ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart

Association Task Force on Practice Guidelines. J. Am. Coll. Cardiol. Oct 16 2002;40(8):1531-1540. Absolute Contraindications to Exercise Stress Testing with hemodynamic compromise stenosis or DVT safe and adequate testing Relative Contraindications to Exercise Stress Testing

Baseline Abnormalities That May Obscure ECG

Changes During Exercise

Measurements During Exercise Stress Testing

Maximal Heart Rate

MHR = 220 ²age (in years)

Metabolic Equivalents (METs)

activities

Physical activityMET

Light intensity activities< 3

sleeping0.9 watching television1.0 walking, 1.7mph (2.7km/h), level ground, strolling, very slow2.3

Moderate intensity activities3 to 6

bicycling, stationary, 50 watts, very light effort3.0

Vigorous intensity activities> 6

jogging, general7.0 rope jumping10.0

The Importance of Functional Capacity

population matter how bad the CAD 2 response

1. Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N.

Engl. J. Med. Mar 14 2002;346(11):793-801.

2. Weiner, D. A., Ryan, T. J., McCabe, C. H., Chaitman, B. R., Sheffield, L. T., Fisher, L. D., et al. (1986). The role of exercise testing in identifying

patients with improved survival after coronary artery bypass surgery.Journal of the American College of Cardiology, 8(4), 741-748

Exercise capacity is a more powerful predictor of mortality among men than other established risk factors for CV disease Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N. Engl. J. Med. Mar 14 2002;346(11):793-801.

Exercise Stress Test Preprocedure Preparation

voltage in inferior leads1 1

Which Protocol to use?

The test protocol should be selected according to the purpose of testing and the individual patient

Exercise protocols

Normal electrocardiographic changes during

exercise

Indications for Terminating Exercise Testing:

Absolute

Indications for Terminating Exercise Testing:

Relative

Clinical Pearls for Exercise Stress Testing

exercise adequately, who have an interpretable ECG, and do not have any contraindications depression observed in multiple lead systems 1 does not localize the area of myocardium that is involved such as it does in

STEMI. 1 ,2

1

2Bonow RO, Braunwald E. Braunwald's heart disease : a textbook of cardiovascular medicine.

9th ed. Philadelphia: Saunders; 2012.

Duke Treadmill Score (DTS)

DTS = exercise time -(5x max ST deviation in mm) -(4 x treadmill angina index) refer patients for further evaluation or intervention patients classified as high or low risk. prognosis: No further evaluation is generally unnecessary prognosis and should be referred for angiography

for another imaging modality (MPI)1Mark DB, Hlatky MA, Harrell FE, Lee KL, Califf RM, Pryor DB. Exercise treadmill score for predicting prognosis

in coronary artery disease. Ann Intern Med. 1987;106:793-800.

2Mark DB, Shaw L, Harrell FE, et al. Prognostic value of a treadmill exercise score in outpatients with

suspected coronary artery disease. N Engl J Med. 1991;325:849-853.http://www.zunis.org/Duke%20Treadmill%20Score%20-

%20CAD%20Predictor.htm

NUCLEAR MYOCARDIAL

PERFUSION IMAGING

´72 18.( 25 127 72 18.("µ

Myocardial Perfusion Imaging:

Nuclear Stress Test

that is taken up and retained in viable cardiac tissue quantifiable 3-D map of myocardial perfusion Photo source: Ballard-+HUQMQGH]·V SHUVRQMO SORPR ŃROOHŃPLRQ

Myocardial Perfusion Imaging

What are we looking for with MPI?

patient Shawet al. J Am Coll Cardiol Img.2014; 7(6):593-604. doi: 10.1016/j.jcmg.2013.10.021 Stress Rest anterior inferiorseptumlateral anterior inferiorapexbase baseapex lateralseptumShort Axis View

Vertical Long-

Axis View

Horizontal

Long-Axis View

Shawet al. J Am Coll Cardiol Img.2014; 7(6):593-604. doi: 10.1016/j.jcmg.2013.10.021

Who is a Good Candidate for Nuclear MPI

Optimal Patient for Nuclear MPI

Nuclear MPI: Limitations

Pharmacologic Stress Testing Agents:

Selective A2a Receptor Agonists and Adenosine

Adenosine

coronary vasodilatation blocks

Pharmacologic Stress Testing Agents:

Dobutamine

BP, and CO.

STRESS ECHOCARDIOGRAPHY

Stress Echocardiography

function at rest and during stress

Exercise Stress Echo with Moderate Ischemia

Shawet al. J Am Coll Cardiol Img.2014; 7(6):593-604. doi: 10.1016/j.jcmg.2013.10.021

Dobutamine Stress Protocol

Stress Echocardiography: Limitations

Comparison of Tests for Diagnosis of CAD

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CASE STUDIES

Case Study # 1

Associated nausea

What test is the most appropriate for the patient?

Outcome Case # 1

exercise

Case study #2

Not associated with exertion

What test is the most appropriate for the patient?

Outcome

defects identified.

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modalities modalities testing agents assessment, diagnosis, clinical management and prognosisquotesdbs_dbs15.pdfusesText_21