Biosafety permit

  • What are BSL-2 requirements?

    BSL-2 laboratories are used to study moderate-risk infectious agents or toxins that pose a moderate danger if accidentally inhaled, swallowed, or exposed to the skin.
    Design requirements for BSL-2 laboratories include hand washing sinks, eye washing stations, and doors that close and lock automatically..

  • What are the levels of containment?

    The four biosafety levels are BSL-1, BSL-2, BSL-3, and BSL-4, with BSL-4 being the highest (maximum) level of containment.
    There are additional specific rules and designations for animal research (ABSL), agricultural research (BSL-Ag), and other types of research..

  • What is containment in biosafety?

    Biocontainment is a component of biorisk management.
    The overall objective of biocontainment is to confine an infectious organism or toxin, thereby reducing the potential for exposure to laboratory workers or persons outside the laboratory, and the likelihood of accidental release to the environment..

  • Who can handle biological materials at the University of Toronto?

    In order to work with biological materials at the University of Toronto, Principal Investigators must have a Biosafety Permit approved by the University.
    The required information must be typed on the application form..

  • Biohazard levels, more commonly referred to as “biological safety levels” or “biosafety levels,” are classifications of safety precautions necessary to be applied in the clinical microbiology laboratory depending on specific pathogens handled when performing laboratory procedures.
  • In order to work with biological materials at the University of Toronto, Principal Investigators must have a Biosafety Permit approved by the University.
    The required information must be typed on the application form.
A biosafety permit documents a researcher's facilities, personnel, materials and scope of research. An approved biosafety permit ensures compliance with all regulatory agencies and allows for the release of research funds from the Office of Research Services.
A University of Toronto Biosafety Permit is required for any research or teaching activities which involve the use or manipulation of biological materials and 
Biosafety permits are required if human tissues, cells, blood or other fluids are removed for the purposes of further study. If the testing and work is all performed by an accredited lab (like LifeLabs) then biosafety is not required.
What is a biosafety permit? A biosafety permit documents a researcher's facilities, personnel, materials and scope of research. An approved biosafety permit ensures compliance with all regulatory agencies and allows for the release of research funds from the Office of Research Services.

Do you need a permit to export biological materials?

Whatever the reason, it is important to remember that import, interstate movement, and export (in some cases) of biological materials are tightly regulated by various federal agencies and may require permits.

How do I apply for a biocontainment permit?

If you plan to apply for any of the following permits, please contact the Biosafety Office (974-1938 or 974-5547) prior to your application submission.
We can assist with form preparation and implementation of specific biocontainment procedures that may apply to your work.

What level of biosafety is a recombinant DNA lab?

Labs operating at biosafety level 3 and above:

  • BSL-3/ABSL-3
  • BSL-4/ABSL-4 Labs working with recombinant DNA (rDNA) materials at biosafety level 2 (BSL-2/ABSL-2) and above.
    The Biological Safety Program administers this permitting.

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