Furthermore, studies have shown that there are direct links between reduction in brain tissue volume and cognitive decline (Sluimer et al., 2008), that decline in brain tissue volume and increased cerebrospinal fluid (CSF) longitudinally are associated with lower cognitive performance (Cardenas et al., 2011), and that
Furthermore, studies have shown that there are direct links between reduction in brain tissue volume and cognitive decline (Sluimer et al., 2008), that decline in brain tissue volume and increased cerebrospinal fluid (CSF) longitudinally are associated with lower cognitive performance (Cardenas et al., 2011), and that
Hence, a larger 'brain reserve' might delay and slow down cognitive decline compared to a smaller 'brain reserve'. In humans, whole brain volume and/or the volume of certain structures were smaller in individuals with age-related cognitive diseases (Ritchie et al., 2015; Wolf et al., 2004).
Our findings show that cognitive ability in youth is a strong predictor of estimated prior and measured current brain volume in old age but that these effects IntroductionMethodResultsDiscussion
