Macromolecular crystallography

  • What are the basics of macromolecular crystallography?

    Definition.
    Given its capability of delivering atomic-level detailed models of large and complex protein structures, macromolecular crystallography, based on X-ray diffraction, is the dominating structure determination technique in structural biology and drug discovery..

  • What is a macromolecular crystal?

    Macromolecular crystals are mainly composed of solvent.
    The protein occupies the remaining volume so that the entire crystal is in many ways an ordered gel with extensive interstitial spaces through which solvent and other “small” molecules may freely diffuse (see, e.g., Rosenberger, 1986; McPherson, 1990)..

  • What is macromolecular crystallography?

    Macromolecular crystallography (MX) is the dominant means of determining the three-dimensional structures of biological macromolecules, but the method has reached a critical juncture..

  • What is the meaning of macromolecular crystallography?

    Macromolecular crystallography (MX) is the dominant means of determining the three-dimensional structures of biological macromolecules, but the method has reached a critical juncture..

  • The Macromolecular Crystallography (MX) beamlines are general purpose crystallography instruments for determining chemical and biological structures.
    The MX1 beamline is a bending-magnet beamline with stability and ease of use for high-throughput crystallography projects.
Annotation Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Google BooksOriginally published: 1997
Macromolecular Crystallography is a technique used to study biological molecules such as proteins, viruses and nucleic acids (RNA and DNA) to a resolution  News and announcementsStructural Molecular BiologyUsers GuideForms

What is macromolecular crystallography?

Macromolecular Crystallography is a technique used to study biological molecules such as proteins, viruses and nucleic acids (RNA and DNA) to a resolution higher than ~5Å

This high resolution helps elucidate the detailed mechanism by which these macromolecules carry out their functions in living cells and organisms

What is the crystalline architecture of a macromolecule?

Therefore, researchers increasingly focus on nucleation, the most complicated stage in the crystallization of macromolecules, and on elevating crystal’s quality

At last, most of the researchers are on the belief that the crystalline architecture of a macromolecule is similar to its architecture in solution

Macromolecular Crystallography is a technique used to study biological molecules such as proteins, viruses and nucleic acids (RNA and DNA) to a resolution higher than ~5Å. This high resolution helps elucidate the detailed mechanism by which these macromolecules carry out their functions in living cells and organisms.

Categories

Maud crystallography
Nano crystallography
Crystallographic names
Crystallography in nanotechnology
Crystallography of nanomaterials
Crystallography parameters
Crystallography patterns
Crystallography parameter definition
Crystallography pay rate
Crystallographic parameters
Crystallographic parameters in kmno4 are
Pandda crystallography
Crystallographic patterns
Patterson crystallography
Parrot crystallography
Crystallographic packing efficiency
Crystallographic packing fraction
Crystallography diffraction pattern
Raman crystallography
Radio crystallography