Cytology genetics and infectious diseases in hindi

  • Cytology, Genetics And Infectious Diseases (Zoology) Book for UP

    Cytology deals with the study of cells, their origin, structure, function and pathology.
    It makes use of light or electron microscopic methods for the study of morphology, and as a means to diagnose or test for cancer and other diseases.
    Genetics deals primarily with the patterns of inheritance of specific traits..

  • Infectious diseases exert significant selective genetic pressure, and the genes that are involved in immune response are exquisitely diverse [3].
    These observations suggest a strong role for host genetic variability in the susceptibility to exogenous pathogens.

Are infectious diseases a global threat?

Infectious diseases are an ever-present global threat

In this Review, Kwok, Mentzer and Knight discuss our latest understanding of how human genetics influence susceptibility to disease

Does genetic technology influence susceptibility to infectious diseases?

As genetic technology has developed, mirroring other disease syndromes, a raft of genetic loci influencing susceptibility to infectious diseases have been discovered through genome-wide association studies (GWAS), including for HIV infection, TB, hepatitis and malaria8(Table 1)

What is the role of genetic variation in infectious disease GWAS?

Of particular interest in infectious disease GWAS has been the role of genetic variation at the locus encoding HLA genes in determining the individual response to infection, given the role of encoded MHC molecules in binding and presenting antigens and thus determining which antigens are ‘seen’ by the immune system (Box 1)


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