Cytology atrophy

  • What are atrophic cells?

    Atrophy is defined as a decrease in the size of a tissue or organ due to cellular shrinkage; the decrease in cell size is caused by the loss of organelles, cytoplasm and proteins..

  • What does atrophy mean on a Pap smear result?

    A diagnosis of atrophic pattern is indicative of low numbers of neutrophils.
    As the Papanicolaou test diagnosis of atrophic vaginitis does not correlate with clinical symptoms, a single diagnostic term that does not suggest a disease process would more reliably communicate cytology findings to clinicians..

  • What is an atrophic smear pattern?

    A diagnosis of atrophic pattern is indicative of low numbers of neutrophils.
    As the Papanicolaou test diagnosis of atrophic vaginitis does not correlate with clinical symptoms, a single diagnostic term that does not suggest a disease process would more reliably communicate cytology findings to clinicians..

  • What is an atrophic smear?

    From a diagnostic perspective, atrophic smears may be interpreted as positive malignant smears in postmenopausal and occasionally in premenopausal women.
    However, rarely a high grade or malignant smear might be rendered as the atrophic smear.Jan 10, 2017.

  • What is cytology atrophy?

    Atrophic menopausal smear (atrophic pattern)
    The cytopathologic features of the atrophic cervico-vaginal smear are: a variable cellularity, with miniature polygonal to round squamous cells with orangeophilic cytoplasm and dot like pyknotic nuclei (red atrophy or pseudoparakeratosis)..

  • What is the meaning of atrophic smear?

    From a diagnostic perspective, atrophic smears may be interpreted as positive malignant smears in postmenopausal and occasionally in premenopausal women.
    However, rarely a high grade or malignant smear might be rendered as the atrophic smear.Jan 10, 2017.

  • Squamous atrophy is characterised by thinning of the cervical squamous epithelium without evidence of cellular differentiation.
    Atrophy occurs in states of low oestrogen such as menopause or in women taking oral contraceptives with low levels of oestrogen.
  • The smear pattern of an atrophic smear with marked inflammation comprises sheets of and dissociated parabasal cells.
    Loss of fragile cytoplasm of the thin atrophic and relatively dry epithelium leads to plenty bare nuclei throughout the smear.
Jul 17, 2023AtrophyIncreased number of parabasal cells and basal cells, which form sheets and syncytial-like aggregates or hyperchromatic crowded groups 
Atrophic menopausal smear (atrophic pattern) The cytopathologic features of the atrophic cervico-vaginal smear are: a variable cellularity, with miniature polygonal to round squamous cells with orangeophilic cytoplasm and dot like pyknotic nuclei (red atrophy or pseudoparakeratosis).

How are atrophic changes diagnosed?

While healthcare providers typically rely on examinations to diagnose atrophic changes or GSM, they may do the following tests to rule out other conditions:

  1. Pap test

Urine sample.
Ultrasound.
Vaginal pH (acid test).
Vaginal infection testing.
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How can physiologic changes affect vaginal atrophy in postmenopausal women?

Education regarding the physiologic changes associated with vaginal atrophy should help clinicians identify and encourage implementation of appropriate treatment regimens in postmenopausal women.
As women progress through peri- and postmenopause, significant hormonal insufficiency leads to vaginal and urogenital symptoms.

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What is vaginal atrophy?

Vaginal atrophy is a condition where the lining of your vagina gets drier and thinner.
This results in itching, burning and pain during sex, among other symptoms.
The condition also includes ,urinary tract problems such as:

  1. urinary tract infections (UTIs) and urinary incontinence

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