Difference between cytology and pap smear

  • What is the difference between Pap smear and liquid-based cytology?

    LBC can be a better alternative to conventional smear because of lower rate of unsatisfactory smears.
    Furthermore, residual LBC sample is available to perform HPV DNA testing.
    LBC with concomitant HPV testing can prove to be more effective in high-resource setting..

Liquid-based cervical cytology was developed to improve the diagnostic reliability of Papanicolaou (Pap) smears. Conventional Pap smears can have false-negative and false-positive results because of inadequate sampling and slide preparation, and errors in laboratory detection and interpretation.

Can a Pap test detect cancer?

A Pap test also sometimes finds conditions that are not cancer, such as:

  1. infection or inflammation

The HPV/Pap cotest uses an HPV test and Pap test together to check for both high-risk HPV and cervical cell changes.
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What is a Pap Smear used for?

A Pap smear is used to screen for cervical cancer.
The Pap smear is usually done in conjunction with a pelvic exam.
In women older than age 30, the Pap test may be combined with a test for human papillomavirus (HPV) — a common sexually transmitted infection that can cause cervical cancer.

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What Is Cytology?

Cytology (also known as cytopathology) involves examining cells from bodily tissues or fluids to determine a diagnosis.
A certain kind of physician, called a pathologist, will look at the cells in the tissue sample under a microscope and look for characteristics or abnormalities in the cells.
Since cytology only examines cells, which are so tiny, p.

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What is the difference between liquid based cytology and Pap smear?

Choice of screening test also depends on the cytology laboratory in which the samples are processed; although liquid-based cytology is more expensive, its ease of use allows laboratories to process slides more quickly and efficiently.
For these reasons, liquid-based cytology has virtually replaced conventional Pap smears in the United States.


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