Difference between cytology and hpv testing

  • Is a cytology test the same as HPV?

    The human papillomavirus (HPV) test checks cells for infection with high-risk HPV types that can cause cervical cancer.
    The Pap test (also called a Pap smear or cervical cytology) collects cervical cells so they can be checked for changes caused by HPV that may—if left untreated—turn into cervical cancer.Apr 27, 2023.

  • What is HPV primary screening and cytology?

    By knowing who has high-risk HPV, we can make sure that we monitor the virus and find any cell changes early, before they potentially develop into cervical cancer.
    HPV primary screening is a more accurate test than cytology.
    This means it is better at detecting cell changes overall, as well as detecting them earlier..

  • What is the best diagnostic test for HPV?

    The important methods to diagnose HPV infection are:

    Colposcopy and acetic acid test.Biopsy.DNA test (PCR, Southern Blot Hybridization, In Situ Hybridization)Pap smear..

  • What is the cytology of HPV infection?

    The cytology test can find abnormal cervical cells, which could lead to cervical cancer over time, and an HPV test detects HPV infection of the cervix.
    The HPV test can be used alone for cervical cancer screening or at the same time as the cytology test (known as cotesting) for those aged ≥30 years to 65 years..

  • The important methods to diagnose HPV infection are:

    Colposcopy and acetic acid test.Biopsy.DNA test (PCR, Southern Blot Hybridization, In Situ Hybridization)Pap smear.
  • The HPV test looks for the virus (human papillomavirus) that can cause cell changes on the cervix.
    The Pap test (or Pap smear) looks for precancers, cell changes on the cervix that might become cervical cancer if they are not treated appropriately.
However, a negative HPV test is more reassuring than a negative cytological test, as the cytological test has a greater chance of being falsely negative, which could lead to delays in receiving the appropriate treatment.
The sensitivity of cytology for CIN3+ was less than 50% compared to more than 95% for HPV testing. Furthermore, cytology varied widely between centres while HPV had comparable sensitivity in all the sites.

Screening Options

There are now three recommended options for cervical cancer screening in individuals aged 30–65 years: primary hrHPV testing every 5 years, cervical cytology alone every 3 years, or co-testing with a combination of cytology and hrHPV testing every 5 years Table.
1) All three screening strategies are effective, and each provides a reasonable balance .


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