Imprint cytology to

  • What is imprint cytology used for?

    A valuable information on morphological details of the cell can be obtained through imprint cytology.
    Though it has some pitfalls, it is still considered to be one of the best methods as it provides an excellent cytological clarity in fresh surgical specimens..

  • What is the role of imprint cytology in the diagnosis of ovarian neoplasms?

    Thus imprint cytology is an effective cytological method in the diagnosis of ovarian neoplasms.
    Knowledge of specific cytological features for each tumor type helps in accurate diagnosis which in turn is valuable in immediate appropriate treatment and management of patients with benign or malignant neoplasms..

  • The specimen is transferred to a glass slide, where it is smeared between two slides.
    Touch imprints involve applying the slide surface directly to the lesion or tissue, a method that tends to preserve the relationship of cells to one another and is popular for assessing lymph node lesions and small core biopsies.
Imprint cytology is simple and rapid technique for tissue diagnosis. Imprint is a touch preparation in which tissue is touched on the slide and it leaves behind its imprint in the form of cells on glass slide; studies are made after proper staining.
Thus, imprint cytology plays a significant role in the quick diagnosis of the lesion. It provides crisp cytological details. Cost effectiveness, rapid results  AbstractUses

Can cytologically well-differentiated tumours be diagnosed by the imprint method?

Used intraoperatively, the imprint method can provide valuable information when frozen-section interpretation is equivocal.
However, cytologically well-differentiated tumours and tumours with a dense fibrous stroma, constituting 6% of the cases in the present series, cannot be diagnosed by this method.

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Is cytology a good method?

Though it has some pitfalls, it is still considered to be one of the best methods as it provides an excellent cytological clarity in fresh surgical specimens.
This article shares knowledge about the … Imprint cytology J Pharm Bioallied Sci. 2015 Apr;7(Suppl 1):S207-8.doi:

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Is Imprint cytology a reliable method for lung and pleural malignancies?

Conclusion Imprint cytology is an easy, rapid, and reliable method that has a high sensitivity and specificity in the diagnosis of lung and pleural malignancies compared with histopathology.

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What is the role of Imprint cytology in intraoperative diagnosis?

Role of imprint cytology in intraoperative diagnosis:

  1. value and limitations

Imprints prepared from fresh surgical specimens give excellent cytological clarity.
Used intraoperatively, the imprint method can provide valuable information when frozen-section interpretation is equivocal.
Hormonal imprinting (HI) is a phenomenon which takes place at the first encounter between a hormone and its developing receptor in the critical periods of life and determines the later signal transduction capacity of the cell.
The most important period in mammals is the perinatal one, however this system can be imprinted at weaning, at puberty and in case of continuously dividing cells during the whole life.
Faulty imprinting is caused by drugs, environmental pollutants and other hormone-like molecules present in excess at the critical periods with lifelong receptorial, morphological, biochemical and behavioral consequences.
HI is transmitted to the hundreds of progeny generations in unicellulars and to a few generations also in mammals.

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