Definitions of cytologic smear. a thin tissue or blood sample spread on a glass slide and stained for cytologic examination and diagnosis under a microscope. synonyms: cytosmear, smear..
Direct smears as described above.
Cytocentrifuge smears, which are prepared using the cytocentrifuge method.
This method concentrates the material and is especially advantageous when few cells are present in a large amount of fluid, such as pleural or peritoneal fluids.
Centrifuge smears using membrane filters..
In cytological smear, the sample is either smeared on a glass slide or made on a monolaye, and it is subsequently stained with the following stains- Papanicolaou, Diff quick and heamatoxylin and eosin.
Samples of CB are fixed in 10% neutral buffered formalin and then treated as a tissue block..
Direct smears are sometimes the only available materials for diagnosis
In the absence of cell block, immunoperoxidase studies can be performed on the direct smears and provide useful information for diagnosis (Fig
1 2 )If the smears are cellular, the cells can be peeled off and transferred to multiple slides for a panel of immunostains
Additional preparations: If flocculent material is present, collect some of the material and prepare an additional slide using the smear technique described for cytology samples
along with a direct filmFill a centrifuge tube with 5 mL fresh, well-mixed urine and then centrifuge it on the urine setting (or 400 x g)
The direct spreading makes a cytological smear of the specimen onto a glass slide
Forward smears are the easiest and quickest of the various methods to move cells from a fresh specimen to a sheet
Specific smears are scrapings, brushings, Tzank smears, smears for viral inclusion
Clinical personnel often make smears at collection time
