One aspect that makes biochemistry and molecular biology difficult is that they draw on knowledge from other disciplines – most heavily from biology, which provides the relevance; but also chemistry, which provides the molecular understanding; and to a certain extent mathematics and physics (see Figure 2.2)..
Biochemists investigate the mechanisms of drug actions; engage in viral research; conduct research pertaining to organ function; or use chemical concepts, procedures, and techniques to study the diagnosis and therapy of disease and the assessment of health..
At its most basic, biochemistry is the study of the chemical processes occurring in living matter..
Biochemistry is the application of chemistry to the study of biological processes at the cellular and molecular level.
It emerged as a distinct discipline around the beginning of the 20th century when scientists combined chemistry, physiology, and biology to investigate the chemistry of living systems..
It emerged as a distinct discipline around the beginning of the 20th century when scientists combined chemistry, physiology, and biology to investigate the chemistry of living systems..
Must study.
Biochemistry deals with study of chemical basis of life in living organism including:
The inhibitory constant (Ki) and the IC50 of a drug that is known to cause inhibition of a cytochrome P450 (CYP) enzyme have to do with the concentration needed to reduce the activity of that enzyme by half.
More specifically the Ki is reflective of the binding affinity and the IC50 is more reflective of the functional strength of the inhibitor for a drug.
Potassium iodide is described as an inorganic chemical compound which is denoted by the chemical formula - KI.
This compound is defined as a metal-halide salt featuring an ionic bond between potassium cation (K+) and iodide anion (I–).
This compound is colorless to white, and it appears as cubical crystals or white or powder granules.
