What are atypical epithelial cells in urine?
Having a large number of epithelial cells in your urine can signal an infection such as a UTI.
It can also occur due to a serious condition, such as kidney or liver problems or certain types of cancer..
What are the findings in urine cytology?
This test looks at a sample of your urine to see if it contains abnormal cells.
The test is used to diagnose cancers of the urinary tract.
These include cancers of the kidney, bladder, ureter, and urethra.
A healthcare provider called a pathologist looks at the cells from your urine sample under a microscope..
What can cause atypical cells in urine cytology?
Abnormal cells in the urine may be a sign of inflammation of the urinary tract or cancer of the kidney, ureters, bladder, or urethra.
Abnormal cells may also be seen if the person has had radiation therapy near the bladder, such as for prostate cancer, uterine cancer, or colon cancer..
What is a atypical cell?
Atypical cells mean that the cells are not entirely normal.
Normal cells go through quite a few changes before they become cancerous.
The cells may not necessarily become cancer cells.
The cells might not change further.
Or they may die off or go back to normal..
What is the specificity of urine cytology?
The moderate sensitivity of cytology is complemented by its very high specificity (range of most studies: 95% to 100%).
False-positive results, in other words, are uncommon.
Some investigators report finding no false-positive results in their studies36,44; others describe rates ranging from 1.3% to 15%..
- Of the 31 patients with a history of urolithiasis, 3 patients (9.7%) had urothelial neoplasia on follow-up.
Urolithiasis was more likely to cause AUTF in VU than urothelial neoplasia (28.8% vs 10.0%; P \x26lt;0.0001).
Urolithiasis can cause cytologic atypia, including some atypical features found in urothelial carcinoma. - When do I collect my sample? Please note: The first urine passed in the morning is unsuitable for cytological analysis.
A urine sample taken mid-morning would be suitable.
Collect the urine into the clean, dry container provided and screw on the top tightly to stop any leakage.
