Exfoliative cytology why

  • - Exfoliative cytology - The specialist examines the cells shed by the body or technically scraped from other body tissues. - Interventional cytology - The sample cells are obtained through piercing the body.
  • What is the purpose of exfoliative cytology?

    Exfoliative cytology is a non-invasive test that uses the Tzanck smear technique to identify disease by examining the structure of cells obtained from scraped samples..

  • What is the reason for cytology?

    Cytology is the exam of a single cell type, as often found in fluid specimens.
    It's mainly used to diagnose or screen for cancer.
    It's also used to screen for fetal abnormalities, for pap smears, to diagnose infectious organisms, and in other screening and diagnostic areas..

  • What tests use exfoliative cytology?

    Respiratory/exfoliative cytology, which includes bronchial washing, sputum, bronchoalveolar lavage, and bronchial brushing cytology.
    Those are commonly used to detect pulmonary infections and malignancies.
    Urinary cytology: Urine cytology, bladder washing, and brushing cytology..

  • Why exfoliative cytology is performed?

    Exfoliative cytology is a simple procedure designed to detect the presence of malignancy through analysis of cell structure..

  • Its use has thus far been more effective in the diagnosis of cancer of the lung, urinary bladder, esophagus, stomach, rectum and sigmoid colon, and the pleural and peritoneal fluids.
  • Specifically, exfoliative cytology performed on oral cancers has high false negative rates, which can exceed 30%.
    Furthermore, the effectiveness of exfoliative cytology for detecting dysplasia is even more doubtful, with false negative rates reported as high as 63%.
Role of exfoliative cytology can be regarded as a standard technique in screening of oral pathologies. [7] Cytomorphometric analysis or image analysis of exfoliated cells has also been suggested as a key approach to define and identify the cellular and nuclear changes in cytological smears.

Which skin cancers are false positive in exfoliative cytology?

In these analyses, we considered any other skin cancers (for example melanomas or cSCCs) in the 'disease negative' group that exfoliative cytology incorrectly identified as BCCs to be false positive results.


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