Does atypia mean cancer?
On occasion you may see a report from a Pap test or tissue biopsy stating "atypical cells present." This might cause you to worry that this means cancer, but atypical cells aren't necessarily cancerous.
Many factors can make normal cells appear atypical, including inflammation and infection..
What causes atypical cells in cytology?
Many factors can make normal cells appear atypical, including inflammation and infection.
Even normal aging can make cells appear abnormal..
What does atypical mean in cytology?
Atypical urothelial cells: This means that the pathologist found some abnormalities in your urine sample, but the cells weren't abnormal enough to be considered cancer.
Suspicious for high-grade urothelial carcinoma: This means that the pathologist found abnormal cells in your urine sample that might be cancer.May 5, 2022.
What does atypical mean on a pathology report?
Learn more about reading a pathology report.
Atypical: Cells that are not normal but are not cancerous.
Atypical cells could become a cancer over time or may increase a person's risk of cancer..
What is an atypical cell?
Atypical cells mean that the cells are not entirely normal.
Normal cells go through quite a few changes before they become cancerous.
The cells may not necessarily become cancer cells.
The cells might not change further.
Or they may die off or go back to normal..
What is the characteristic of atypical cells?
Nuclear & cytoplasmic features in atypical cells: marked pleomorphism and high nuclear and cytoplasmic ratio with pale and angulated cytoplasm (Papanicolaou's stain \xd7 550).
Atypical cells with irregular nuclear margins and nuclear hyperchromasia (Papanicolaou's stain \xd7 1375)..
What is the difference between atypical and suspicious cells?
Atypical urothelial cells: This means that the pathologist found some abnormalities in your urine sample, but the cells weren't abnormal enough to be considered cancer.
Suspicious for high-grade urothelial carcinoma: This means that the pathologist found abnormal cells in your urine sample that might be cancer.May 5, 2022.
- Atypical: Cells that are not normal but are not cancerous.
Atypical cells could become a cancer over time or may increase a person's risk of cancer.
Hyperplasia: An abnormal increase of cells in a tissue or organ.
Hyperplasia may increase the risk of developing some types of cancer. - The overall sensitivity and specificity of urine cytology were 48.9% and 83.0%, respectively.
When the atypical category was considered part of the positive category, the overall sensitivity increased to 72.2%, whereas the specificity decreased to 60.7%.