Advantages of liquid based cytology for pap smear

  • What are the advantages of liquid based cytology over Pap smear?

    LBC can be a better alternative to conventional smear because of lower rate of unsatisfactory smears.
    Furthermore, residual LBC sample is available to perform HPV DNA testing.
    LBC with concomitant HPV testing can prove to be more effective in high-resource setting..

  • What are the advantages of Pap stain in cytology?

    It yields a polychromatic, transparent staining reaction with crisp nuclear and cytological features, which can be easily interpreted by a trained pathologist. [2] The Pap stain has been most frequently used for screening of cervical cancer..

  • What are the advantages of using the liquid based Pap test method?

    Improved preservation of the cellular sample.
    Cells sampled and then immediately immersed in liquid fixative transport media show, on average, better fixation, and thus better visual preservation, than will smeared cellular material on a conventional slide..

  • What are the main advantages of moving from conventional cytology to liquid based cytology?

    The main advantages of moving to LBC are: A reduction in number of unsatisfactory smears.
    Quicker lab turnaround time.
    The ability to use same sample for HPV..

  • What is a liquid based cytology Pap smear test?

    What is the Liquid Based Cytology (LBC) test exactly? Liquid-based cytology (LBC) is a cervical cancer screening technique that inspects cells by dissolving them in liquid.
    This method is less invasive than the conventional Pap smear test.
    The LBC test is also known as ThinPrep.Aug 2, 2021.

  • What is an advantage of the liquid based PAP method?

    The liquid-based processes generally improve cellular visualization via decreases in physiologic obscuring factors such as blood or inflammation.
    The cells in conventional smears may be obscured, leading to unsatisfactory or limited specimens when such factors are present..

  • What is liquid based Pap smear method?

    A clinician will place a speculum into the woman's vagina and identify the cervix.
    The liquid-based method involves collecting cells from the transformation zone of the cervix by using a brush and transferring the cells to a vial of liquid preservative..

  • A clinician will place a speculum into the woman's vagina and identify the cervix.
    The liquid-based method involves collecting cells from the transformation zone of the cervix by using a brush and transferring the cells to a vial of liquid preservative.
  • It yields a polychromatic, transparent staining reaction with crisp nuclear and cytological features, which can be easily interpreted by a trained pathologist. [2] The Pap stain has been most frequently used for screening of cervical cancer.
  • The main advantages of moving to LBC are: A reduction in number of unsatisfactory smears.
    Quicker lab turnaround time.
    The ability to use same sample for HPV.
However, liquid-based cytology rinses cervical cells in preservatives so that blood and other potentially obscuring material can be separated. It also allows for additional testing of the sample, such as for human papillomavirus (HPV).
In addition, LBC has several other advantages over PAP smear as the material can be used in molecular studies, such as the detection of hrHPV. Moreover, in the long run, LBC is also cost-effective in mass cervical cancer screening, as LBC is needed less frequently than the conventional PAP smear.

Does liquid-based cervical cytology improve the diagnostic reliability of Papanicolaou smears?

Background:

  1. Liquid-based cervical cytology was developed to improve the diagnostic reliability of Papanicolaou (Pap) smears

Conventional Pap smears can have false-negative and false-positive results because of inadequate sampling and slide preparation, and errors in laboratory detection and interpretation.
,

Is LBC better than Pap smear?

In addition, LBC has several other advantages over PAP smear as the material can be used in molecular studies, such as:

  1. the detection of hrHPV

Moreover, in the long run, LBC is also cost-effective in mass cervical cancer screening, as LBC is needed less frequently than the conventional PAP smear.
,

Is liquid based cytology better than conventional Pap smear?

Conclusion:

  1. LBC has been found to be more superior to conventional smears only with respect to lesser number of unsatisfactory smears
  2. but considering the economic implications of LBC
  3. conventional Pap is more feasible in our setting

Keywords:Cervical cancer screening; conventional Pap smear; human papillomavirus; liquid-based cytology.
,

Is Pap smear a good method for cervical cytology?

Conventional Pap smear method has been the mainstay of most of the screening programs for many decades.
However, this technique is not without limitations, and the sensitivity and specificity of cervical cytology are relatively low.


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