[PDF] b cell activation steps quizlet

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  • antigen recognition-B cell exposed to antigen and binds with matching complementary.
  • antigen presentation-B cell displays epitope, Helper T cell binds secretes interleukin.
  • clonal selection= interleukin stimulates B cell to divide.
  • differentiation=become memory or plasma cells.
  • attack- plasma cells secrete antibody.
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  • What are the steps of B cell activation?

    B cells are activated when they encounter an antigen that they recognize. The antigen binds to the B cell's surface receptors, which activates and triggers it to divide and differentiate into an antibody-secreting plasma cell. Plasma cells produce antibodies that bind to the antigen and neutralize it.

  • What is the first step following B cell activation?

    The first step, known as the extrafollicular response, occurs outside lymphoid follicles but still in the SLO. During this step activated B cells proliferate, may undergo immunoglobulin class switching, and differentiate into plasmablasts that produce early, weak antibodies mostly of class IgM.

  • What are B cells activated by quizlet?

    -B-cells are activated by the binding of antigen to receptors on its cell surface which causes the cell to divide and proliferate. Some stimulated B-cells become plasma cells, which secrete antibodies. Others become long-lived memory B-cells which can be stimulated at a later time to differentiate into plasma cells.
  • B cells can be activated by direct binding to an antigen. Once a naive B cell recognizes its target antigen, they form germinal centers with the help of CD4 helper T cells. In the germinal center early stage antibody-secreting B cells undergo isotype switching and transition into a plasma cell.
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