[PDF] b cell antigen presentation

Antigen presentation by B2 cells primarily occurs through the BCR, in which interaction with a BCR-specific antigen leads to B cell activation and proliferation  B cell populations · Antigen processing and · Role of CD4 T cells in antigen Autres questions
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  • What is the presentation of antigen to B cells?

    Like DCs, B cells also participate in antigen presentation, and this can occur through direct or cross presentation. Antigenic peptide-loaded B cells interact with CD4+ as well as CD8+ T cells, leading to their activation and resulting in Th1 and Th2 type immune responses (32–34).

  • How is B cell antigen presentation unique?

    B cells arise from hematopoietic stem cells in the bone marrow and, following maturation, leave the marrow expressing a unique antigen-binding receptor on their membrane. Unlike T cells, B cells can recognize antigens directly, without the need for APCs, through unique antibodies expressed on their cell surface.

  • Are antigen presenting cells B or T?

    B lymphocytes are regarded as professional antigen-presenting cells (APCs) despite their primary role in humoral immunity.
  • Classical antigen presenting cells (APCs) are dendritic cells (DCs) and B cells (10). To mount an immune response, APCs must first recognize and bind their target. To do so, APCs express antigen-specific surface receptors including pattern recognition receptors (PRRs).
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